The Generalized Anxiety Disorder Screener (GAD-7) and the anxiety module of the Hospital and Depression Scale (HADS-A) as screening tools for generalized anxiety disorder among cancer patients

Psycho-oncology
Peter EsserAnja Mehnert

Abstract

Anxiety in cancer patients may represent a normal psychological reaction. To detect patients with pathological levels, appropriate screeners with established cut-offs are needed. Given that previous research is sparse, we investigated the diagnostic accuracy of 2 frequently used screening tools in detecting generalized anxiety disorder (GAD). We used data of a multicenter study including 2141 cancer patients. Diagnostic accuracy was investigated for the Generalized Anxiety Disorder Screener (GAD-7) and the anxiety module of the Hospital Anxiety and Depression Scale (HADS-A). GAD, assessed with the Composite International Diagnostic Interview for Oncology, served as a reference standard. Overall accuracy was measured with the area under the receiver operating characteristics curve (AUC). The AUC of the 2 screeners were statistically compared. We also calculated accuracy measures for selected cut-offs. Diagnostic accuracy could be interpreted as adequate for both screeners, with an identical AUC of .81 (95% CI: .79-.82). Consequently, the 2 screeners did not differ in their performance (P = .86). The best balance between sensitivity and specificity was found for cut-offs ≥7 (GAD-7) and ≥8 (HADS-A). The officially recommended thre...Continue Reading

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Citations

Jun 10, 2020·Journal of Cancer Survivorship : Research and Practice·Kristen BarrVictoria White
Aug 20, 2019·Oncology Nursing Forum·Marlen Rodriguez-WolfeWilliam F Pirl
Apr 3, 2019·Frontiers in Psychiatry·Jung-Kwang AhnKee-Hong Choi
Aug 2, 2020·Translational Psychiatry·Yuanyuan WangRunsen Chen
Feb 12, 2021·General Hospital Psychiatry·Carol Byrd-BredbennerVirginia Quick
Mar 7, 2021·International Journal of Environmental Research and Public Health·Zahra AlsairafiZahraa Jalal
Mar 21, 2021·European Journal of Clinical Nutrition·Vered Kaufman-ShriquiMona Boaz
Apr 2, 2021·Neuropsychiatric Disease and Treatment·Xiao HuangJian-Dong Gao
Apr 21, 2021·International Journal of Clinical Practice·Hamad S AlyamiMusfer S Alyami
May 4, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Johanna T W SnijkersDaniel Keszthelyi
May 4, 2021·Frontiers in Psychology·Abdallah Y NaserHaya Khalil
Jun 8, 2021·Preventive Medicine Reports·Joanna M StreckElyse R Park
Jun 14, 2021·Comprehensive Psychiatry·Anna La SalviaFrancesco Oliva
Jul 16, 2021·Psychotherapie, Psychosomatik, medizinische Psychologie·Malin BockholtSigrun Vehling
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Aug 29, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sebastian W NielsenSusanne O Dalton

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