PMID: 15228182Jul 2, 2004Paper

The genetic background of tumour necrosis factor receptor-associated periodic syndrome and other systemic autoinflammatory disorders

Scandinavian Journal of Rheumatology
S Stjernberg-SalmelaT Pettersson

Abstract

Systemic autoinflammatory disorders are hereditary diseases with symptoms of acute inflammation and a rise in serum acute phase proteins as a consequence, but with no signs of autoimmunity. By the end of the 1990s, four types of hereditary periodic fever had been described in the medical literature: familial Mediterranean fever, hyperimmunoglobulinemia D with periodic fever syndrome (HIDS), tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS) and Muckle-Wells syndrome. Since then, the number of diseases classified as systemic autoinflammatory disorders has increased to eight. In patients of Nordic descent, cases of HIDS and TRAPS have been reported. We provide an overview of the genetic background and main clinical aspects of the different autoinflammatory disorders, with an emphasis on TRAPS.

References

Oct 1, 1968·The American Journal of Medicine·F Bergman, S Warmenius
Sep 1, 1997·Nature Genetics·UNKNOWN French FMF Consortium
Dec 31, 1997·The Journal of Biological Chemistry·F GuesdonJ Saklatvala
Jun 19, 1998·American Journal of Human Genetics·M F McDermottG A Hitman
Apr 25, 2000·BMJ : British Medical Journal·J P Drenth, J W van Der Meer
Jan 4, 2001·Clinical and Diagnostic Laboratory Immunology·I S KlasenJ P Drenth
Dec 14, 2001·The New England Journal of Medicine·J P Drenth, J W van der Meer
Mar 19, 2002·Cellular Signalling·David J MacEwan
Dec 18, 2002·The Journal of Experimental Medicine·Christian StehlikJohn C Reed
Jan 10, 2003·Nucleic Acids Research·Cyril Sarrauste de MenthièreIsabelle Touitou
Mar 21, 2003·Biochemical and Biophysical Research Communications·Junya MasumotoNaohiro Inohara

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Citations

Jan 20, 2006·Journal of Internal Medicine·S Stjernberg-SalmelaT Pettersson

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