The genetic basis of sex determination in grapes.

Nature Communications
Mélanie MassonnetDario Cantu

Abstract

It remains a major challenge to identify the genes and mutations that lead to plant sexual differentiation. Here, we study the structure and evolution of the sex-determining region (SDR) in Vitis species. We report an improved, chromosome-scale Cabernet Sauvignon genome sequence and the phased assembly of nine wild and cultivated grape genomes. By resolving twenty Vitis SDR haplotypes, we compare male, female, and hermaphrodite haplotype structures and identify sex-linked regions. Coupled with gene expression data, we identify a candidate male-sterility mutation in the VviINP1 gene and potential female-sterility function associated with the transcription factor VviYABBY3. Our data suggest that dioecy has been lost during domestication through a rare recombination event between male and female haplotypes. This work significantly advances the understanding of the genetic basis of sex determination in Vitis and provides the information necessary to rapidly identify sex types in grape breeding programs.

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Citations

Aug 28, 2020·Frontiers in Plant Science·Quentin Cronk, Niels A Müller
Nov 6, 2020·Scientific Reports·Miguel J N RamosMargarida Rocheta
Dec 11, 2020·The Plant Journal : for Cell and Molecular Biology·Yi WangZhenchang Liang
Feb 2, 2021·Frontiers in Plant Science·Ana Paula Leite MontalvãoNiels Andreas Müller
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Cheng ZouJason P Londo
May 1, 2021·International Journal of Molecular Sciences·Fabrizio Grassi, Gabriella De Lorenzis
Apr 20, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Aline MuyleJames M A Turner
May 21, 2021·Proceedings of the National Academy of Sciences of the United States of America·Kayoko YamamotoHisayoshi Nozaki
May 13, 2021·The New Phytologist·Djivan PrentoutGabriel A B Marais
Jun 27, 2021·Nature Communications·Alexis GroppiVéronique Decroocq
Sep 28, 2021·The Plant Journal : for Cell and Molecular Biology·Othman Al-DossaryRobert J Henry

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Methods Mentioned

BETA
HiC
PCR
RNA-seq
chip

Software Mentioned

Unzip
Integrative Genomics Viewer ( IGV )
BWA
diff
VariationFiltration ( GATK
R package JASPAR2018
DAmasker
MUMmer
Bioconductor
Plink

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