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The genetic code can cause systematic bias in simple phylogenetic models

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Oct 15, 2008

Simon Whelan

Abstract

Phylogenetic analysis depends on inferential methodology estimating accurately the degree of divergence between sequences. Inaccurate estimates can lead to misleading evolutionary inferences, including incorrect tree topology estimates and poor dating of historical species divergence. P...read more

Mentioned in this Paper

In Silico
Truncation Biases
Likelihood Functions
Phylogeny
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Nucleotides
Open Reading Frames
Amino Acid [EPC]
Paper Details
References
  • References18
  • Citations9
1

The genetic code can cause systematic bias in simple phylogenetic models

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Oct 15, 2008

Simon Whelan

PMID: 18852102

DOI: 10.1098/rstb.2008.0171

Abstract

Phylogenetic analysis depends on inferential methodology estimating accurately the degree of divergence between sequences. Inaccurate estimates can lead to misleading evolutionary inferences, including incorrect tree topology estimates and poor dating of historical species divergence. P...read more

Mentioned in this Paper

In Silico
Truncation Biases
Likelihood Functions
Phylogeny
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Nucleotides
Open Reading Frames
Amino Acid [EPC]
Paper Details
References
  • References18
  • Citations9
1
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