The genetic organisation of the capsule biosynthesis region of Actinobacillus pleuropneumoniae serotypes 1, 6, 7, and 12

Veterinary Microbiology
Stine G JessingØystein Angen

Abstract

The aim of the present study was to investigate the organisation of the genes (cps) involved in biosynthesis the capsular polysaccharide (CPS) of Actinobacillus pleuropneumoniae serotypes 6, 7, and 12 and to compare these to the corresponding genes previously described in other A. pleuropneumoniae serotypes. In serotypes 6 and 7 the sequenced DNA regions comprised five and four open reading frames, respectively, designated cps6ABCDE and cps7ABCD, whereas the sequenced DNA region in serotype 12 comprised only two open reading frames designated cps12AB. At the amino acid level, CpsA, CpsB, and CpsC of A. pleuropneumoniae serotypes 2, 6, 7, and 8 contained a high degree of homology. At the amino acid level Cps6D revealed a high degree of homology to Cps8D, whereas Cps7D contained a high degree of homology to the Cps2D. The deduced gene product of the partially sequenced cps6E gene showed no homology to any deduced gene products of any cps genes of A. pleuropneumoniae investigated so far. None of the deduced gene products of the cps genes involved in encapsulation of A. pleuropneumoniae serotypes 2, 6, 7, and 8 revealed homology to the deduced gene products of the cps genes of serotypes 1, 5A, and 12. For some genes, a local homolo...Continue Reading

References

Nov 1, 1991·Microbial Pathogenesis·T J Inzana
Jan 1, 1996·Annual Review of Microbiology·I S Roberts
Apr 1, 1997·BioTechniques·R W HarrisonG Kampo
Oct 14, 1998·FEMS Microbiology Letters·J Y ChungB Adler
Jun 1, 2000·Nature·H OchmanE A Groisman
Dec 4, 2001·Veterinary Microbiology·P J BlackallJ Frey
May 23, 2003·Infection and Immunity·Aloka B BandaraThomas J Inzana
Mar 1, 1964·The Journal of Experimental Medicine·R E SHOPE
Jul 21, 2004·Briefings in Bioinformatics·Sudhir KumarMasatoshi Nei
Sep 15, 2004·Journal of Clinical Microbiology·Jennifer A SchuchertS Jessing
Mar 5, 2005·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Malcolm B PerryEvgeny Vinogradov

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Citations

Dec 27, 2013·The Journal of Veterinary Medical Science·Hiroya ItoHirofumi Yuzawa
Aug 31, 2010·Journal of Bacteriology·Zhuofei XuRui Zhou
Aug 31, 2010·Journal of Bacteriology·Bujie ZhanFrank Panitz
Dec 17, 2014·The Journal of Veterinary Medical Science·Hiroya Ito, Masuo Sueyoshi
Nov 13, 2014·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Hiroya Ito, Atsuko Matsumoto

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