PMID: 6278419Jan 22, 1982Paper

The genome of Plasmodium falciparum. I: DNA base composition

Nucleic Acids Research
Y PollackJ Golenser

Abstract

Some structural properties of the DNA of Plasmodium falciparum were studied thoroughly using several techniques. Its G+C content was found to be extremely low (17-19%), the lowest reported for a living organism. The DNA seems to be composed only of the four major bases as no methylated bases were detected. This DNA had a Tm value of 62.5 degrees C and its denaturation profile showed no marked intramolecular heterogeneity.

References

Apr 1, 1971·Parasitology·W E GutteridgeD H Williamson
Aug 1, 1968·The Journal of protozoology·C J Walsh, I W Sherman
Nov 7, 1980·Science·A Razin, A D Riggs
Jan 1, 1980·Journal of Immunological Methods·J J HesslingN L Levy
Feb 9, 1981·FEBS Letters·Y GruenbaumA Razin
Mar 25, 1980·Nucleic Acids Research·A Razin, S Razin
Jun 1, 1962·Journal of Molecular Biology·C L SCHILDKRAUTP DOTY

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Citations

Jul 1, 1983·Molecular and Biochemical Parasitology·J B Dame, T F McCutchan
Apr 1, 1984·Molecular and Biochemical Parasitology·J Franco Da SilveiraO Mercereau-Puijalon
Feb 1, 1985·Molecular and Biochemical Parasitology·D H WilliamsonB U Qiang
Jan 15, 1988·Molecular and Biochemical Parasitology·M G PetersonD J Kemp
Jan 15, 1988·Molecular and Biochemical Parasitology·J G WesselingJ G Schoenmakers
Aug 1, 1988·Molecular and Biochemical Parasitology·J G WesselingJ G Schoenmakers
Feb 1, 1988·Molecular and Biochemical Parasitology·S C NichollsA A Holder
Feb 1, 1989·Molecular and Biochemical Parasitology·W B LiJ Inselburg
Feb 1, 1991·Molecular and Biochemical Parasitology·T Triglia, D J Kemp
Jul 1, 1994·Molecular and Biochemical Parasitology·J M Favaloro, D J Kemp
Jul 1, 1996·Molecular and Biochemical Parasitology·J B DameE B Werner
Jan 1, 1983·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·S TungpradabkulY Yuthavong
Oct 1, 1991·Research in Immunology·J C BaraleC Braun-Breton
Nov 13, 2003·Acta Tropica·S WongratanacheewinS Sirisinha
Apr 14, 2005·International Journal for Parasitology·Ross L Coppel, Casilda G Black
Dec 2, 2000·Microbes and Infection·S Bowman, P Horrocks
Mar 1, 1991·Journal of Helminthology·R SermswanS Sirisinha
Aug 1, 1988·Parasitology·N RothsteinT V Rajan
Apr 4, 2006·Nature Reviews. Microbiology·Taco W A KooijAndrew P Waters
Oct 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·H RubinB S Cooperman
Aug 7, 2007·Journal of Biomolecular Structure & Dynamics·Víctor SabbíaHéctor Musto
Feb 25, 1989·Nucleic Acids Research·A G Brownlee
Aug 15, 1998·Nucleic Acids Research·K J DecheringJ A Leunissen
Feb 4, 2014·PloS One·Graeme J M CowanDavid R Cavanagh

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