The genome of pseudocowpoxvirus: comparison of a reindeer isolate and a reference strain

The Journal of General Virology
Maria HautaniemiColin J McInnes

Abstract

Parapoxviruses (PPV), of the family Poxviridae, cause a pustular cutaneous disease in sheep and goats (orf virus, ORFV) and cattle (pseudocowpoxvirus, PCPV and bovine papular stomatitis virus, BPSV). Here, we present the first genomic sequence of a reference strain of PCPV (VR634) along with the genomic sequence of a PPV (F00.120R) isolated in Finland from reindeer (Rangifer tarandus tarandus). The F00.120R and VR634 genomes are 135 and 145 kb in length and contain 131 and 134 putative genes, respectively, with their genome organization being similar to that of other PPVs. The predicted proteins of F00.120R and VR634 have an average amino acid sequence identity of over 95%, whereas they share only 88 and 73% amino acid identity with the ORFV and BPSV proteomes, respectively. The most notable differences were found near the genome termini. F00.120R lacks six and VR634 lacks three genes seen near the right terminus of other PPVs. Four genes at the left end of F00.120R and one in the middle of both genomes appear to be fragmented paralogues of other genes within the genome. VR634 has larger than expected inverted terminal repeats possibly as a result of genomic rearrangements. The high G+C content (64%) of these two viruses along ...Continue Reading

References

Nov 1, 1990·Virology·S J GoebelE Paoletti
Feb 1, 1989·The Journal of General Virology·P D GershonD N Black
Mar 1, 1987·Virology·A A MercerA J Robinson
Feb 1, 1981·Journal of Virological Methods·J EspositoJ Obijeski
Aug 1, 1995·Virology·R F MassungJ J Esposito
Jan 1, 1994·Journal of Virology·D J LyttleA J Robinson
Mar 15, 1993·FEBS Letters·S N ShchelkunovL S Sandakhchiev
Mar 13, 2001·Annual Review of Immunology·K W MooreA O'Garra
Jan 25, 2003·Annual Review of Immunology·Bruce T SeetGrant McFadden
Feb 8, 2003·Virology·Norihito UedaAndrew A Mercer
Jun 14, 2003·Journal of Virology·Chris UptonRachel L Roper
Jun 21, 1963·Science·A E FRIEDMAN-KIENW G BANFIELD
Dec 4, 2003·The Journal of General Virology·Kathryn ThomasColin J McInnes
Dec 6, 2003·Proceedings of the National Academy of Sciences of the United States of America·Bruce T SeetStephen B Fleming
Dec 9, 2003·Proceedings of the National Academy of Sciences of the United States of America·Aoife McLysaghtBrandon S Gaut
Dec 13, 2003·Journal of Virology·G DelhonD L Rock
Jan 14, 2004·The Journal of General Virology·Caroline GubserGeoffrey L Smith
Aug 6, 2004·Endocrine Reviews·Napoleone Ferrara
Jul 19, 2005·Virus Genes·Andrew A MercerNorihito Ueda

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Citations

Dec 31, 2010·The New England Journal of Medicine·Amira A RoessInger K Damon
Jan 19, 2013·The Onderstepoort Journal of Veterinary Research·Alessandra ScagliariniCheryl M McCrindle
Feb 13, 2015·Virusdisease·Tuba Çiğdem OğuzoğluMehmet Tolga Tan
Nov 21, 2014·BMC Research Notes·Edith LedermanYu Li
Mar 26, 2015·Viruses·Stephen B FlemingAndrew A Mercer
Feb 19, 2015·Viruses·Michael H HerbertAndrew A Mercer
Aug 28, 2015·The Journal of Veterinary Medical Science·Kaizhao ZhangZhangyong Ning
Feb 13, 2013·Zoonoses and Public Health·A A RoessI K Damon
Feb 24, 2015·The Journal of General Virology·Schirin FriederichsMathias Büttner
Oct 29, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Sherry L HallerStefan Rothenburg
Mar 23, 2015·Virus Genes·Andrea PeraltaGuido A König
Jan 1, 2014·Virus Research·Schirin FriederichsMathias Büttner
Jul 30, 2011·Virus Research·Maria HautaniemiColin J McInnes
May 8, 2016·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Mateus Laguardia-NascimentoAntônio Augusto Fonseca Júnior
Dec 30, 2014·Stroke; a Journal of Cerebral Circulation·Seyoung LeeChristopher G Sobey
Aug 9, 2017·PLoS Pathogens·Sushil KhatiwadaDaniel L Rock
Nov 12, 2015·Frontiers in Microbiology·Xuelin ChiShihua Wang
Jul 5, 2018·Frontiers in Veterinary Science·Andrea PeraltaGuido A König
Oct 25, 2016·The Veterinary Quarterly·Mateus Laguardia-NascimentoAntônio Augusto Fonseca Júnior
Nov 20, 2019·Emerging Infectious Diseases·Julien AndreaniBernard La Scola
Dec 16, 2017·PLoS Pathogens·Ponnuraj NagendraprabhuDaniel L Rock
Apr 12, 2017·The Onderstepoort Journal of Veterinary Research·Ahmad OryanAli Mohammadi
Nov 21, 2017·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Gunilla BlomqvistJean-Francois Valarcher
Mar 1, 2016·Virology Journal·Esayas GelayeCharles Euloge Lamien
Apr 5, 2020·Journal of Clinical Medicine·Jordan R YaronAlexandra R Lucas
Nov 8, 2020·Archives of Virology·Gabriel Augusto de Oliveira LopesJenner Karlisson Pimenta Dos Reis
Jun 4, 2021·Frontiers in Veterinary Science·Helena CostaMorten Tryland

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