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The genome-wide determinants of human and chimpanzee microsatellite evolution

Genome Research

Jan 1, 2008

Yogeshwar D KelkarKateryna D. Makova

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Abstract

Mutation rates of microsatellites vary greatly among loci. The causes of this heterogeneity remain largely enigmatic yet are crucial for understanding numerous human neurological diseases and genetic instability in cancer. In this first genome-wide study, the relative contributions of i...read more

Mentioned in this Paper

Tetranucleotide Repeats
Mutagenesis Process
Mutation Abnormality
Pan troglodytes
Genome
Pan Genus
Short Tandem Repeat
Evolution, Molecular
Mutagenesis Procedure
Isochores
128
Paper Details
References
  • References44
  • Citations79
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The genome-wide determinants of human and chimpanzee microsatellite evolution

Genome Research

Jan 1, 2008

Yogeshwar D KelkarKateryna D. Makova

PMID: 18032720

DOI: 10.1101/gr.7113408

Abstract

Mutation rates of microsatellites vary greatly among loci. The causes of this heterogeneity remain largely enigmatic yet are crucial for understanding numerous human neurological diseases and genetic instability in cancer. In this first genome-wide study, the relative contributions of i...read more

Mentioned in this Paper

Tetranucleotide Repeats
Mutagenesis Process
Mutation Abnormality
Pan troglodytes
Genome
128

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Paper Details
References
  • References44
  • Citations79
12345...

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