The genomic CDS sandbox: An assessment among domain experts

Journal of Biomedical Informatics
Ayesha AzizBrandon M Welch

Abstract

Genomics is a promising tool that is becoming more widely available to improve the care and treatment of individuals. While there is much assertion, genomics will most certainly require the use of clinical decision support (CDS) to be fully realized in the routine clinical setting. The National Human Genome Research Institute (NHGRI) of the National Institutes of Health recently convened an in-person, multi-day meeting on this topic. It was widely recognized that there is a need to promote the innovation and development of resources for genomic CDS such as a CDS sandbox. The purpose of this study was to evaluate a proposed approach for such a genomic CDS sandbox among domain experts and potential users. Survey results indicate a significant interest and desire for a genomic CDS sandbox environment among domain experts. These results will be used to guide the development of a genomic CDS sandbox.

References

Dec 13, 2005·American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice·Edward AbrahamsMike Silver
Jan 11, 2007·Journal of the American Medical Informatics Association : JAMIA·Jerome A OsheroffDon E Detmer
Jan 9, 2012·Journal of Biomedical Informatics·Daniel R MasysHoward P Levy
Aug 28, 2012·Journal of the American Medical Informatics Association : JAMIA·Brandon M Welch, Kensaku Kawamoto
Oct 19, 2012·Journal of the American Medical Informatics Association : JAMIA·Howard R StrasbergJames J Cimino
Sep 21, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Casey Lynnette OverbyGeorge Hripcsak
Sep 28, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Peter Tarczy-HornochYaping Yang
Sep 28, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Abel N KhoM Geoffrey Hayes
Sep 28, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Joseph L Kannry, Marc S Williams
Jun 17, 2014·Journal of Biomedical Informatics·Brandon M WelchKensaku Kawamoto
Sep 10, 2014·Journal of the American Medical Informatics Association : JAMIA·L Ohno-Machado
Nov 21, 2014·Journal of Personalized Medicine·Brandon M WelchKensaku Kawamoto

❮ Previous
Next ❯

Citations

Mar 24, 2016·Computers in Biology and Medicine·Manuel GrañaSebastian Rios
Feb 18, 2017·International Journal of Molecular Sciences·Karen Y HeMax M He
Sep 29, 2019·World Neurosurgery·Mohamad BydonLola B Chambless

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.