DOI: 10.1101/505628Dec 23, 2018Paper

The genomic landscape of western South America: Andes, Amazonia and Pacific Coast

BioRxiv : the Preprint Server for Biology
Chiara BarbieriLars Fehren-Schmitz

Abstract

Studies of Native South American genetic diversity have helped to shed light on the peopling and differentiation of the continent, but available data are sparse for the major ecogeographic domains. These include the Pacific Coast, a potential early migration route; the Andes, home to the most expansive complex societies and to one of the most spoken indigenous language families of the continent (Quechua); and Amazonia, with its understudied population structure and rich cultural diversity. Here we explore the genetic structure of 177 individuals from these three domains, genotyped with the Affymetrix Human Origins array. We infer multiple sources of ancestry within the Native American ancestry component; one with clear predominance on the Coast and in the Andes, and at least two distinct substrates in neighboring Amazonia, with a previously undetected ancestry characteristic of northern Ecuador and Colombia. Amazonian populations are also involved in recent gene-flow with each other and across ecogeographic domains, which does not accord with the traditional view of small, isolated groups. Long distance genetic connections between speakers of the same language family suggest that languages had spread not by cultural contact alo...Continue Reading

Related Concepts

Cell Differentiation Process
Pan American Health Organization
Societies
Proximal
Isolation Aspects
Laboratory Culture
Home Environment
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Single Nucleotide Polymorphism

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