The genomic medicine model: an integrated approach to implementation of family health history in primary care

Personalized Medicine
Lori A OrlandoGenomedical Connection

Abstract

As an essential tool for risk stratification, family health history (FHH) is a central component of personalized medicine; yet, despite its widespread acceptance among professional societies and its established place in the medical interview, its widespread adoption is hindered by three major barriers: quality of FHH collection, risk stratification capabilities and interpretation of risk stratification for clinical care. To overcome these barriers and bring FHH to the forefront of the personalized medicine effort, we developed the genomic medicine model (GMM) for primary care. The GMM, founded upon the principles of the Health Belief Model, Adult Learning Theory and the implementation sciences, shifts responsibility for FHH onto the patient, uses information technology (MeTree©) for risk stratification and interpretation, and provides education across multiple levels for each stakeholder, freeing up the clinical encounter for discussion around personalized preventive healthcare plans. The GMM has been implemented and optimized as part of an implementation-effectiveness hybrid pilot study for breast/ovarian cancer, colon cancer and thrombosis, and risk for hereditary cancer syndromes in two primary care clinics in NC, USA. This ...Continue Reading

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Citations

Oct 25, 2017·Zdravstveno Varstvo·Zalika Klemenc-KetišAntonija Poplas Susič
Oct 25, 2017·Zdravstveno Varstvo·Zalika Klemenc-KetišGunnar Tschudi Bondevik
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Oct 28, 2019·PloS One·Sarina MadhavanSusanne B Haga
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Mar 13, 2014·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Lori A OrlandoGeoffrey S Ginsburg
Mar 5, 2016·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Lori A OrlandoGeoffrey S Ginsburg

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Software Mentioned

MeTree

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