The genomics of insecticide resistance: insights from recent studies in African malaria vectors

Current Opinion in Insect Science
Chris S ClarksonAlistair Miles

Abstract

Over 80% of the world's population is at risk from arthropod-vectored diseases, and arthropod crop pests are a significant threat to food security. Insecticides are our front-line response for controlling these disease vectors and pests, and consequently the increasing prevalence of insecticide resistance is of global concern. Here we provide a brief overview of how genomics can be used to implement effective insecticide resistance management (IRM), with a focus on recent advances in the study of Anopheles gambiae, the major vector of malaria in Africa. These advances unlock the potential for a predictive form of IRM, allowing tractable feedback for stakeholders, where the latest field data and well parameterised models can maximise the lifetime and effectiveness of available insecticides.

Citations

Apr 10, 2021·Nature Reviews. Genetics·Daniel E NeafseyBronwyn L MacInnis
Aug 11, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·M Senthil KumarBhavna Gupta

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Methods Mentioned

BETA
genotyping

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