The George Edelstyn memorial lecture: radiation in the management of malignant soft tissue tumours

Clinical Oncology : a Journal of the Royal College of Radiologists
H D Suit

Abstract

Consistently good results in patients with sarcoma of soft tissue are more likely if they are managed by a sarcoma team in a centre which sees large numbers of such patients. The results of treatment of 258 patients at Massachusetts General Hospital (1971-1986) by radiation with surgery are described. The rationale for combining radiation and surgery is considered. Local control rates (actuarial at 5 years) are 86% and 91% for radiation administered postoperatively and pre-operatively respectively. In the most recent period, 1980-1986, the results were 92% and 97% respectively (63 and 82 patients). Preoperative radiation treatment is judged to be more effective than postoperative radiation, especially for the larger sarcomas. Currently, several strategies are being employed in the management of patients with sarcoma of soft tissues: radical ablative surgery, surgery combined with radiation (pre- or postoperatively, and or intra-operatively), and surgery combined with radiation and intra-arterial chemotherapy. High local control rates are being achieved by these diverse treatment methods. There is an obvious need to assess the cosmetic and functional results achieved by the different treatment methods so as to determine the most...Continue Reading

References

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Citations

Feb 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·T WiklundI Elomaa
Jun 9, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A M Eggermont
Jan 30, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M ArnoldK R Trott
Dec 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·S DischeE Aird
Mar 1, 1992·Clinical Oncology : a Journal of the Royal College of Radiologists·P TeoS F Leung
Dec 1, 1990·AORN Journal·P H Berger, H M Saul
Jul 2, 2008·History of Psychiatry·John A Mills

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