PMID: 628813Feb 1, 1978Paper

The glomerular filtration rate determined with 99mTc-DTPA and a portable cadmium telluride detector

Scandinavian Journal of Clinical and Laboratory Investigation
N RossingP L Frederiksen

Abstract

In twenty-two patients with 51Cr-EDTA renal clearance (glomerular filtration rate) values of 36-141 ml/min, the final plasma disappearance rate constant of i.v. injected 99mTc-DTPA (Sn) was found to be very close to that of 51Cr-EDTA determined from 180 to 300 min after injection. The disappearance of i.v. injected 99mTc-DTPA (Sn) was also recorded from the body surface by means of a low weight cadmium telluride detector (CRN, Strasbourg, France) and commercially available stationary or portable tape recorders. The disappearance rate constant of 99mTc-DTPA as determined externally from 30 min was comparable to that in plasma determined from 180-300 min. The external rate constant could be converted to plasma clearance by means of one plasma 99mTc-activity determination 180 min after injection. The calculated values agreed with the conventionally determined 51Cr-EDTA clearance values. The portability of the detector system allows it to be used to estimate alterations in GFR during the measurement due to changes in physical conditions such as posture, exercise, etc.

References

Sep 1, 1976·The British Journal of Radiology·A J HilsonM N Maisey
Sep 1, 1976·Journal of Applied Physiology·J Bojsen, S Vadstrup
Nov 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·J Bröchner-Mortensen
Jun 1, 1969·Scandinavian Journal of Clinical and Laboratory Investigation·J Bröchner-MortensenN Rossing
Mar 1, 1971·Radiology·H L AtkinsP Richards
Jan 1, 1959·The Journal of Clinical Investigation·L G RAISZR L SCHEER

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Citations

Nov 1, 1988·Scandinavian Journal of Clinical and Laboratory Investigation·M Rehling
Feb 1, 1985·Clinical Physiology·J Brøchner-Mortensen
May 5, 2020·Scandinavian Journal of Clinical and Laboratory Investigation·Jane A SimonsenThomas L Andersen
Dec 1, 1986·Clinical Physiology·A B Christensen, S Groth
Sep 11, 2019·Scandinavian Journal of Clinical and Laboratory Investigation·Trine B AndersenLars J Petersen
Jan 1, 1988·Urological Research·C S WorthleyR Hickman
Mar 5, 2021·Journal of Nephrology·Emmanuelle Vidal-PetiotMartin Flamant
Nov 1, 1992·Critical Reviews in Oncology/hematology·G Daugaard, U Abildgaard
Jul 1, 1982·Seminars in Nuclear Medicine·L R Chervu, M D Blaufox
Oct 1, 1982·Seminars in Nuclear Medicine·E V Dubovsky, C D Russell

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