PMID: 4290549Apr 1, 1966Paper

The glycerol teichoic acid from the cell wall of Bacillus stearothermophilus B65

The Biochemical Journal
A J Wicken

Abstract

1. A glycerol teichoic acid has been extracted from cell walls of Bacillus stearothermophilus B65 and its structure examined. 2. Trichloroacetic acid-extractable teichoic acid accounted for 68% of the total cell-wall phosphorus and residual material could be hydrolysed to a mixture of products including those characteristic of glycerol teichoic acids. 3. The extracted polymer is composed of glycerol, phosphoric acid, d-glucose and d-alanine. 4. Hydrolysis of the polymer with alkali gave glycerol, 1-O-alpha-d-glucopyranosylglycerol and its monophosphates, glycerol mono- and di-phosphate, as well as traces of a glucosyldiglycerol triphosphate and a glucosylglycerol diphosphate. 5. The teichoic acid is a polymer of 18 or 19 glycerol phosphate units having alpha-d-glucopyranosyl residues attached to position 1 of 14 or 15 of the glycerol residues. 6. The glycerol residues are joined by phosphodiester linkages involving positions 2 and 3 in each glycerol. 7. d-Alanine is in ester linkage to the hydroxyl group at position 6 of approximately half of the glucose residues. 8. One in every 13 or 12 polymer molecules bears a phosphomonoester group on position 3 of a glucose residue, the possible significance of which in linkage of the pol...Continue Reading

Citations

Jun 28, 2007·Medical Teacher·Ducksun Ahn, Sowon Ahn
Aug 1, 1991·Regulatory Toxicology and Pharmacology : RTP·G B Gori, N Mantel
Jun 1, 1975·Acta Pathologica Et Microbiologica Scandinavica. Section B, Microbiology·G S JohnsenP Oeding
Jun 1, 1973·Bacteriological Reviews·K W Knox, A J Wicken
Jul 26, 1968·Biochemical and Biophysical Research Communications·W D Grant, A J Wicken
Oct 5, 1966·Biochemical and Biophysical Research Communications·I T Forrester, A J Wicken
Mar 1, 1968·Bacteriological Reviews·S M Friedman
May 1, 1973·Biochimie·H TabaudE Vilkas

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