Abstract
The neuroanatomical distribution and morphology of neurons that produce gonadotropin-releasing hormone (GnRH) in the brain of the postpubertal male Djungarian hamster was studied using light microscopic immunocytochemistry. Analysis of every section from the rostral olfactory tubercle to the medial basal hypothalamus indicate 356 +/- 37 immunoreactive GnRH perikarya per brain (mean +/- SE; n = 4 brains). Over 90% of GnRH cell bodies were found in 6 brain regions; the largest number of somata were located in the medial preoptic area followed by the diagonal band, lateral hypothalamus, lateral preoptic area, lateral septum and anterior hypothalamus. Morphologically, two predominant types of GnRH neurons were identified: unipolar GnRH cells with an ovoid soma and only a single distinct process (about 40% of all GnRH neurons), and bipolar cells with a fusiform-shaped perikaryon. Overall and in most brain regions, the ratio of unipolar to bipolar GnRH perikarya was 2:3 or greater. A significant proportion of GnRH neurons had an unusually "thick" process(es) that exited the soma and tapered gradually. GnRH fibers were evident in most sections, forming dense plexuses in the arcuate nucleus-median eminence, the periventricular region o...Continue Reading
Citations
Nov 1, 1992·Cell and Tissue Research·F N ToumiJ Peytevin
Jul 10, 1995·Brain Research·A I KorytkoJ L Blank
Mar 1, 1992·Peptides·Y P Tang, C L Sisk
Jul 1, 1992·Alcohol·R F McGivern, S M Yellon
May 3, 2005·Brain Research·Fabienne AujardMartine Perret
Nov 13, 2001·Neuroscience Letters·R A LeslieF J Ebling
Mar 17, 1999·Brain Research Bulletin·F J EblingM H Hastings
Feb 2, 2000·Brain Research Bulletin·A R KaruriM S Kumar
Aug 24, 2002·The European Journal of Neuroscience·Simon J EvansHuda Akil
Jul 19, 2005·Annual Review of Neuroscience·Mary E Hatten, Nathaniel Heintz
Jul 8, 1993·The Journal of Comparative Neurology·K L Buchanan, S M Yellon
Jan 8, 1994·The Journal of Comparative Neurology·P A MelroseD D French
Sep 27, 2008·Neuroscience·M K OosthuizenC W Coen
Mar 19, 2013·The Journal of Comparative Neurology·Shuzhi ZhouClive W Coen
Jul 14, 2018·The Journal of Comparative Neurology·Katarina MedgerClive W Coen
Sep 24, 1999·Biology of Reproduction·T L McElhinnyL Smale
Jan 23, 1999·Biology of Reproduction·D J BernardF W Turek
Dec 31, 1997·The Journal of Comparative Neurology·J E RobinsonM A Haupt
Jan 15, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Mauricio AvigdorPaul D Heideman