The graft-versus-host reaction in the rabbit spleen. Ultrastructural evidence for two differentiated T-cell lines

Virchows Archiv. B, Cell Pathology Including Molecular Pathology
J E VeldmanF J Keuning

Abstract

Lethally irradiated (900 rads), bone-marrow-protected rabbits were given allogeneic thymocytes intravenously. Autoradiography by means of local splenic infusion of (H3) thymidine revealed progeny of two differentiated T-cell lines. Electron microscopy confirmed these observations in detail. An analogy with cellular immunity reactions in an "isolated T-cell system", performed in draining lymph nodes after a variety of antigenic stimuli is presented. The functional properties of these T-blasts and their lymphoid descendants are discussed.

References

Oct 16, 1978·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·J E VeldmanI Molenaar
Oct 16, 1978·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·J E Veldman, F J Keuning
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Jan 1, 1980·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·J E VeldmanF J Keuning
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Citations

Jan 1, 1980·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·J E VeldmanF J Keuning

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