The green and stable dissolving system based on KOH/urea for homogeneous chemical modification of chitosan

International Journal of Biological Macromolecules
Shichao BiXiguang Chen

Abstract

The novel solvent (0.25 M KOH/0.01 M urea alkaline solution) was used to successfully dissolve chitosan without freezing-thawing cycles, for the first time. The results from XRD, FTIR, and 13CNRM proved that KOH/urea solution could destroy the hydrogen bonds between chitosan chains more efficiently than NaOH/urea solution. The dynamic light scattering, rheology, viscosity and elemental analysis confirmed that the KOH/urea hydrogen-bonded chitosan complex had a better thermal stability at 40 °C, and no obvious deacetylation and degradation appeared in dissolution process. Subsequently, the homogeneous chemical modification of chitosan based on KOH/urea dissolution system solution was conducted at 25 °C. The FTIR and microscopic observation indicated that the carboxymethyl chitosan, N,N,N-trimethyl chitosan and hydroxyl butyl chitosan were synthetized successfully. This work provided a green and stable solvent for homogeneous chemical modification of chitosan.

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Jun 12, 2017·International Journal of Biological Macromolecules·Shichao BiXiguang Chen
Jun 14, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zixian BaoXiguang Chen

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Citations

Jan 19, 2021·Macromolecular Bioscience·Huan XuXiaofang Gao
Nov 11, 2019·International Journal of Biological Macromolecules·Jolleen Natalie I BalitaanKaren S Santiago
Jun 4, 2021·International Journal of Biological Macromolecules·Xiaojie SunChao Feng
Aug 28, 2021·International Journal of Biological Macromolecules·Fang LiShichao Bi

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