The growing teratoma syndrome: a case report and a review of the literature

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
S TangjitgamolC Sheanakul

Abstract

We present the case of a 5-year-old girl with ovarian immature teratoma, which recurred a few months after an incomplete surgical staging. The recurrent masses, located in the upper abdomen and lower pelvis, were accompanied by rise in levels of serum alpha-fetoprotein. The patient and her parents refused surgical resection of these recurrent masses; therefore, chemotherapy was promptly given. After multiple cycles of chemotherapy, all the masses remained stable in size despite normalization of the tumor marker. Subsequent complete resection of the masses showed only mature teratoma (MT) component without any residual malignant germ cell tumor. The patient was disease free for 2 years, when another episode of recurrence developed as a 5-cm mass in the perihepatic area. The third laparotomy revealed a tumor mass, histologically composed of only MT tissue. She is now doing well without any evidence of the disease, 24 months after the last surgery.

References

Feb 1, 1991·British Journal of Urology·G M JefferyG M Mead
Jul 1, 1991·Chest·S G BashedaD P Meeker
Jun 1, 1991·Clinical Radiology·E MoskovicC Parsons
Jun 1, 1986·Obstetrics and Gynecology·D M GershensonF N Rutledge
Nov 1, 1986·Journal of Computer Assisted Tomography·J F LentiniT V Sedlacek
Oct 15, 1982·Cancer·C J LogothetisD E Johnson
Dec 1, 1983·Gynecologic Oncology·J AronowitzA L Kaplan
Jul 19, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F AndréC Théodore
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S. -K. Tay, L. -K. Tan
Sep 7, 2002·The Journal of Obstetrics and Gynaecology Research·Yoshio ItaniKatsutada Hiraoka
Aug 13, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S TangjitgamolS Jesadapatarakul
Aug 21, 2003·European Radiology·Tsutomu InaokaTamio Aburano
Oct 11, 2003·Pediatric Radiology·Katherine NimkinMarc S Lessin

❮ Previous
Next ❯

Citations

Mar 1, 2008·International Journal of Clinical Oncology·Roopa HariprasadMalini Vijayaraghavan
Aug 13, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Vladislav GorbatiyLouis L Pisters
Jul 4, 2009·Taiwanese Journal of Obstetrics & Gynecology·Tsung-Ying HsiehChen-Yang Chou
Apr 1, 2011·The Journal of Obstetrics and Gynaecology Research·Satomi KikawaNoriaki Sakuragi
Jan 27, 2015·Journal of Minimally Invasive Gynecology·Naoya ShigetaTadashi Kimura
May 5, 2011·Case Reports in Medicine·H MrabtiH Errihani
Sep 27, 2014·Journal of Pediatric and Adolescent Gynecology·Paul DaherCaline Rehayem
Apr 9, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Adam PendleburyPeter Grant
Oct 24, 2019·Archives of Pathology & Laboratory Medicine·Kristen V AdamsAli G Saad
Jan 28, 2017·Indian Journal of Surgical Oncology·S P KatariaVidya Jha
Dec 8, 2009·Acta Obstetricia Et Gynecologica Scandinavica·Siriwan TangjitgamolRakchai Buhachat

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Actas urologicas españolas
P Urruchi FernándezL A Rioja Sanz
Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
R KatariaD K Mitra
© 2021 Meta ULC. All rights reserved