Abstract
Fungal genomes range in size from 2.3 Mb for the microsporidian Encephalitozoon intestinalis up to 8000 Mb for Entomophaga aulicae, with a mean genome size of 37 Mb. Basidiobolus, a common inhabitant of vertebrate guts, is distantly related to all other fungi, and is unique in possessing both EF-1α and EFL genes. Using DNA sequencing and a quantitative PCR approach, we estimated a haploid genome size for Basidiobolus at 350 Mb. However, based on allelic variation, the nuclear genome is at least diploid, leading us to believe that the final genome size is at least 700 Mb. We also found that EFL was in three times the copy number of its putatively functionally overlapping paralog EF-1α. This suggests that gene or genome duplication may be an important feature of B. ranarum evolution, and also suggests that B. ranarum may have mechanisms in place that favor the preservation of functionally overlapping genes.
References
Mar 15, 1973·Mycopathologia et mycologia applicata·J Coremans-Pelseneer
Jan 1, 1984·Sabouraudia·V P ChaturvediS Kini
May 1, 1980·Mykosen·H C Gugnani, J I Okafor
Feb 11, 2000·European Journal of Epidemiology·H C Gugnani
May 9, 2003·Nucleic Acids Research·Jochen WilhelmMeinhard Hahn
Apr 1, 1963·The Journal of Cell Biology·C F ROBINOW
Oct 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Patrick J Keeling, Yuji Inagaki
Nov 30, 2005·The Journal of General and Applied Microbiology·Yuuhiko TanabeJunta Sugiyama
Aug 15, 2006·Protist·Gillian H GilePatrick J Keeling
Oct 20, 2006·Nature·Timothy Y JamesRytas Vilgalys
Nov 9, 2006·Nucleic Acids Research·T Ryan GregoryMichael D Bennett
May 10, 2007·Mycologia·Merlin M WhiteJunta Sugiyama
May 25, 2007·BMC Evolutionary Biology·Geoffrey P NoblePatrick J Keeling
May 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Ryoma KamikawaYoshihiko Sako
Jul 1, 2008·Gene·Miako SakaguchiYuji Inagaki
Feb 18, 2009·PloS One·Maureen J KoslowskiJan Wehkamp
Apr 10, 2009·PloS One·Gillian H GilePatrick J Keeling
Jul 15, 2009·The Journal of Heredity·Matthew W Hahn
Apr 8, 2010·Mycopathologia·Arun GoyalSarika Jain
May 29, 2010·Microbiology and Molecular Biology Reviews : MMBR·Soo Chan LeeJoseph Heitman
Jun 17, 2010·Genetics·Cheng XueYun-Xin Fu
Jan 7, 2011·Journal of Tropical Medicine·Mani AnandDhyaneshwari P Ghadage
Mar 3, 2012·G3 : Genes - Genomes - Genetics·Darren AbbeyJudith Berman
Apr 2, 2013·Molecular Phylogenetics and Evolution·Eva NovákováNancy A Moran
Citations
Feb 26, 2014·BMC Evolutionary Biology·Gemma C AtkinsonVasili Hauryliuk
Sep 3, 2014·Genome Biology and Evolution·Kirill V MikhailovVladimir V Aleoshin
Oct 22, 2016·Molecular Phylogenetics and Evolution·Martin CarrFrank Nitsche
Jan 5, 2017·Studies in Mycology·E J van NieuwenhuijzenR A Samson
Dec 26, 2018·Molecular Ecology·Lotus A LofgrenPeter G Kennedy
Apr 26, 2019·Biological Reviews of the Cambridge Philosophical Society·Miguel A Naranjo-Ortiz, Toni Gabaldón
Apr 18, 2020·Biological Reviews of the Cambridge Philosophical Society·Miguel A Naranjo-Ortiz, Toni Gabaldón
Oct 8, 2016·Molecular Ecology·Henrik H De Fine LichtJørgen Eilenberg
Aug 31, 2018·Clinical Microbiology Reviews·Raquel Vilela, Leonel Mendoza
Jan 26, 2020·Microbiome·Nina Montoya-CiriacoYendi E Navarro-Noya
Nov 8, 2020·Applied and Environmental Microbiology·Jacob M WurlitzerMarkus Gressler