The Haemodynamic Instability Score (HIS) for assessment of cardiovascular reactivity in hypertensive and normotensive patients

Journal of Human Hypertension
J E NaschitzD Yeshurun

Abstract

The normal response to postural challenge is characterised by maintenance of relatively stable blood pressure (BP) and heart rate (HR) after 30 sec to 30 min of head-up tilt. The objective of the present study was to determine the degree of instability of cardiovascular responses to postural challenge in normotensive and hypertensive subjects. In the initial phase of the study, two groups of age and sex-matched subjects were assessed: essential hypertension (n = 20) and healthy (n = 37). The BP and HR were recorded at 5-min intervals during the course of the 10-min supine-30-min head-up tilt test (HUTT). We categorised 'BP-change' as the difference between individual BP measurements during HUTT and the last recumbent BP value, divided by latter value. The average and standard deviation (SD) of the recorded BP changes were calculated, and BP changes were plotted along a time curve. A computerised image analyser then calculated the outline ratio (OR) and fractal dimension (FD) values for each of the curves. An identical process evaluated measurements for HR-changes. BP- and HR-changes were then converted into absolute numbers, and the average, SD, OR, and FD were calculated. A multivariate analysis was conducted, evaluating indep...Continue Reading

Citations

Jul 1, 2005·Rheumatology International·Umit Hidir UlasOkay Vural
Jun 17, 2005·Journal of Clinical Monitoring and Computing·Jochanan E NaschitzLuis Gaitini
Mar 1, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Antonio Cuesta-VargasUNKNOWN FibroQoL Study Group
Aug 31, 2010·Journal of the Neurological Sciences·Katalin Réka KovácsLászló Csiba
Jun 6, 2003·QJM : Monthly Journal of the Association of Physicians·R Baschetti
Feb 21, 2004·QJM : Monthly Journal of the Association of Physicians·J E NaschitzE Sabo
Aug 28, 2004·Clinical Science·Jochanan E NaschitzItzhak Rosner
Feb 16, 2013·Journal of Hypertension·Antti J TikkakoskiIlkka H Pörsti

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