PMID: 7015793Mar 1, 1981Paper

The Hamilton depression scale. Evaluation of objectivity using logistic models

Acta Psychiatrica Scandinavica
P BechA Nagy

Abstract

The consistency of the Hamilton Depression Scale (HDS) as a measure of the severity of depressive states has been examined when the scale was used weekly during a trial when imipramine. By use of logistic models (Rasch) the consistency of the HDS has been considered across patient-variables as age, sex, plasma levels of imipramine, and diagnosis. The results showed that the original 17-item HDS was without adequate consistency, i.e. the total score of the sample of items was no one-dimensional measure of depressive states. However, a melancholia subscale of the HDS contained items the total of which can be used to compare patients quantitatively, although in some part of the analysis one of these items showed ceiling effect. It was concluded that the melancholia subscale (containing the items depressed mood, guilt, work and interests, retardation, psychic anxiety, and general somatic symptoms) can form the basis for further improvements in the field of quantitative rating scales for depressive states.

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Citations

Feb 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·P BechJ L Ayuso
Dec 1, 1989·Acta Psychiatrica Scandinavica·A S SørensenT G Bolwig
Jan 1, 1988·Scandinavian Journal of Psychology·H N PetersenB Enig
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Aug 1, 1980·Acta Psychiatrica Scandinavica·P BechO J Rafaelsen
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