PMID: 25743837Mar 7, 2015Paper

The Health Examinees (HEXA) study: rationale, study design and baseline characteristics

Asian Pacific Journal of Cancer Prevention : APJCP
Health Examinees Study Group

Abstract

Korea has experienced rapid economic development in a very short period of time. A mixture of traditional and modern risk factors coexists and the rapid change in non-genetic factors interacts with genetic constituents. With consideration of these unique aspects of Korean society, a large-scale genomic cohort study-the Health Examinees (HEXA) Study-has been conducted to investigate epidemiologic characteristics, genomic features, and gene-environment interactions of major chronic diseases including cancer in the Korean population. Following a standardized study protocol, the subjects were prospectively recruited from 38 health examination centers and training hospitals throughout the country. An interview- based questionnaire survey was conducted to collect information on socio-demographic characteristics, medical history, medication usage, family history, lifestyle factors, diet, physical activity, and reproductive factors for women. Various biological specimens (i.e., plasma, serum, buffy coat, blood cells, genomic DNA, and urine) were collected for biorepository according to the standardized protocol. Skilled medical staff also performed physical examinations. Between 2004 and 2013, a total of 167,169 subjects aged 40-69 yea...Continue Reading

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Citations

Dec 8, 2015·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Hwi-Won LeeDaehee Kang
Feb 6, 2017·Genomics & Informatics·Sungkyoung ChoiTaesung Park
Oct 27, 2017·International Journal of Environmental Research and Public Health·Claire E KimDaehee Kang
Jul 27, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Minkyung KimBoyoung Park
Apr 7, 2018·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Boyoung ParkEun Sook Lee
Oct 31, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Sangah ShinDaehee Kang
Jun 14, 2018·BMC Public Health·Claire E KimDaehee Kang
Feb 14, 2020·Scientific Reports·Sejin KimJung Eun Lee
Aug 17, 2020·Journal of Epidemiology and Community Health·Seong-Ah Kim, Sangah Shin
Oct 10, 2020·Journal of Cancer Prevention·Junghyun Yoon, Boyoung Park
Jan 21, 2021·Journal of General Internal Medicine·Jae Young KimJung Tak Park
Feb 24, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Woohyeun KimEung Ju Kim
May 19, 2020·Obesity Research & Clinical Practice·Jeeyoo LeeJong-Koo Lee
Apr 26, 2021·Journal of the Academy of Nutrition and Dietetics·Seong-Ah KimSangah Shin

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