The heterogeneity of mild traumatic brain injury: Where do we stand?

Brain Injury : [BI]
Andrée TellierIan Gilmour Stiell

Abstract

To explore the heterogeneity of mild traumatic brain injury (mTBI). Hospital-based prospective follow-up study of 125 patients with mTBI sub-divided into 'severity' sub-groups on the basis of GCS scores (GCS of 15 = mild sub-group; GCS of 13-14 = moderate sub-group). Post-traumatic amnesia (PTA) duration (30 minutes used as a cut-off) was also used to define group membership for secondary analyses. The follow-up assessment consisted of a brief neuropsychological battery as well as measures of neurobehavioural functioning, community integration and post-concussive symptomatology. CT scanning was also obtained when clinically relevant. The two mTBI sub-groups, as defined by GCS scores, did not differ with respect to post-concussive symptomatology, neurobehavioural symptoms, neuropsychological performance or CT scan abnormalities. In contrast, when group membership was redefined on the basis of PTA, the two sub-groups differed significantly with respect to intracranial abnormalities and report of aggressive or disinhibited behaviours at the 6-month mark. While the notion of heterogeneity in mTBI was not supported when severity was based on GCS scores, there was partial support when PTA duration was used as a measure of severity.

References

May 1, 1978·Perception & Psychophysics·R W Proctor
Sep 1, 1990·Neurosurgery·D H WilliamsH M Eisenberg
Jul 13, 1974·Lancet·G Teasdale, B Jennett
Sep 1, 1981·Neurosurgery·R W RimelJ A Jane
Aug 1, 1997·Journal of Neurosurgery·J N HsiangW S Poon
Jun 1, 1997·Journal of Clinical and Experimental Neuropsychology·L M Binder
Dec 17, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·S Fleminger
Jun 26, 1999·The Journal of Head Trauma Rehabilitation·C PaniakJ Nagy
Aug 26, 1999·Brain Injury : [BI]·A TellierM Brennan-Barnes
Apr 12, 2001·Brain Injury : [BI]·L J Miller, J Donders
Aug 16, 2001·The Journal of Nervous and Mental Disease·J F Friedland, D R Dawson
May 7, 2002·Journal of Clinical and Experimental Neuropsychology·Chris PaniakDouglas Schmidt
Nov 8, 2002·Archives of Physical Medicine and Rehabilitation·Eric M UmileRosette C Plotkin
Feb 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·S H A ChenG D Hutchins
Sep 1, 1959·Journal of Experimental Psychology·L R PETERSON, M J PETERSON
Jan 7, 2004·Annals of Emergency Medicine·Robert L Wears
Apr 16, 2004·Journal of Rehabilitation Medicine·Jörgen BorgUNKNOWN WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury
Apr 16, 2004·Journal of Rehabilitation Medicine·Linda J CarrollUNKNOWN WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury
Aug 4, 2004·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Shauna KashlubaJulianna Nagy
Jan 26, 2005·The Journal of Head Trauma Rehabilitation·Ronald Ruff
May 17, 2005·Journal of the International Neuropsychological Society : JINS·Rodney D VanderploegHeather G Belanger
May 24, 2006·The Journal of Head Trauma Rehabilitation·Richard E KennedyAngelle M Sander
Aug 11, 2007·Journal of Clinical and Experimental Neuropsychology·Rodney D VanderploegAndres M Salazar
Aug 19, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·S MearesJ E Marosszeky
Dec 15, 2007·Journal of the International Neuropsychological Society : JINS·Erin D Bigler

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Citations

May 3, 2012·Brain Imaging and Behavior·Sara B Rosenbaum, Michael L Lipton
Mar 4, 2014·Journal of Neurotrauma·Kirsi Holli-HeleniusJuha Ohman
Sep 4, 2012·British Journal of Neurosurgery·Kerim BeseogluDaniel Hänggi
Jun 21, 2013·Emergency Medicine Journal : EMJ·Helen SeeleyPeter Hutchinson
Jul 26, 2014·NeuroImage. Clinical·Cyrus EierudStephen M LaConte
Oct 7, 2015·Frontiers in Human Neuroscience·Rose D BharathBharat B Biswal
Jun 17, 2015·Current Pain and Headache Reports·Tad Seifert, Victoria Shipman
Jun 6, 2014·The Journal of Head Trauma Rehabilitation·Ashley SeigerEllen Deibert
Nov 24, 2017·The Indian Journal of Medical Research·Ashok MunivenkatappaJamuna Rajeswaran
Mar 13, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Stefan PiantellaBradley J Wright
Feb 27, 2020·The Journal of Trauma and Acute Care Surgery·Patrick T DelaplainJeffry Nahmias
Jul 25, 2020·Brain Injury : [BI]·Leslie Weaver JohnsonSusan Phillips
Apr 23, 2021·Integrative and Comparative Biology·Daniel J TobianskyMatthew J Fuxjager
Jan 14, 2020·Journal of Neurosurgical Anesthesiology·Heung Kan Ma, John F Bebawy
Sep 17, 2021·American Journal of Speech-language Pathology·Jessica BrownKelly Knollman-Porter

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