Abstract
The present study retrospectively analyses the prevalence of late diagnosis in patients with newly-diagnosed HIV infection in Lodz, Poland from January 2009 to December 2016, and assesses the predictive factors associated with late presenters. Late presentation is defined as a diagnosis of HIV with a CD4 count<350 cells/μL, or the occurrence of an AIDS- defining event, regardless of the CD4 cell count. Two hundred and fifty-nine (62.86%) patients were late presenters, 178 of whom (68.72%) were advanced late presenters (CD4 cell count below 200 cells/μL). Multivariate factors associated with late HIV presentation included referral from physician for HIV testing (OR: 3.95, 95% CI 2.42-6.46), older age (OR: 1.81, 95% CI: 1.38-2.38) and route of HIV transmission. Heterosexual patients (OR 1.98, 95% CI: 1.01-3.90), active drug users (OR: 3.49, 95% CI: 1.63-7.48) and patients who did not report the route of transmission (OR: 4.29, 95%: CI 1.45-12.62) were more likely to present late than MSM subjects. In conclusion, the majority of HIV-infected patients are still diagnosed late. There is a need for expanded testing not only in MSM group, in which HIV prevalence is the highest, but also in intravenous drug users, or among subjects who...Continue Reading
References
Mar 27, 1998·The New England Journal of Medicine·F J PalellaS D Holmberg
Jul 20, 2002·Lancet·Matthias EggerUNKNOWN ART Cohort Collaboration
Dec 4, 2004·AIDS·Caroline A SabinMargaret A Johnson
Dec 17, 2004·International Journal of STD & AIDS·K ManaviG Scott
May 14, 2008·Current HIV Research·George PanosMatthew E Falagas
Dec 6, 2008·AIDS Patient Care and STDs·Kimberly B UlettMichael J Mugavero
Feb 6, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kathleen FalsterUNKNOWN Australian HIV Observational Database
Jun 22, 2010·HIV Medicine·A AntinoriUNKNOWN European Late Presenter Consensus Working Group
Jul 16, 2010·BMC Public Health·Kamalika MojumdarSanjay Mendiratta
Jul 7, 2011·AIDS Research and Therapy·Patricia Garcia de OlallaUNKNOWN HIV Surveillance Group
Mar 30, 2013·BMC Public Health·Laura CamoniUNKNOWN regional representatives of the HIV Surveillance System
Oct 19, 2013·PLoS Medicine·Amanda MocroftUNKNOWN Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study in EuroCoord
Mar 26, 2014·AIDS Patient Care and STDs·Mary Jo TrepkaSpencer Lieb
Jul 21, 2015·The New England Journal of Medicine·UNKNOWN INSIGHT START Study GroupJames D Neaton
Jan 6, 2016·BMJ Open·Eline L M Op de CoulUNKNOWN ATHENA National Observational HIV Cohort
Citations
Apr 17, 2020·AIDS Research and Human Retroviruses·Vasileios PetrakisDimitrios Papazoglou
Jan 8, 2021·HIV Medicine·E JabłonowskaJ D Kowalska
Jul 10, 2019·The Lancet. HIV·Sandeep PrabhuNagalingeswaran Kumarasamy
Sep 9, 2021·AIDS Care·Zahra GheibiMostafa Dianatinasab