Abstract
The evolution of organ transplantation has produced results so successful that many transplant programs commonly see recipients with medical risks, which in the past, would have prohibited transplantation. The Eighth Annual American Society of Transplant Surgeons State-of-the-Art Winter Symposium focused on the high-risk recipient. The assessment of risk has evolved over time, as transplantation has matured. The acceptance of risk associated with a given candidate today is often made in consideration of the relative value of the organ to other candidates, the regulatory environment, and philosophical notions of utility, equity, and fairness. In addition, transplant programs must balance outcomes, transplant volume, and the costs of organ transplantation, which are impacted by high-risk recipients. Discussion focused on various types of high-risk recipients, such as those with coronary artery disease, morbid obesity, and hepatitis C; strategies to reduce risk, such as down-staging of hepatocellular carcinoma and treatment of pulmonary hypertension; the development of alternatives to transplantation; and the degree to which risk can or should be used to define candidate selection. These approaches can modify the impact of recipie...Continue Reading
References
Nov 1, 1995·World Journal of Surgery·R PichlmayrG Tusch
Mar 14, 1996·The New England Journal of Medicine·V MazzaferroL Gennari
Dec 24, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P MathurinM O Bitker
Jun 11, 1999·Annals of Surgery·R M GhobrialR W Busuttil
Mar 17, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·M FacciutoP A Sheiner
Nov 10, 2000·General Hospital Psychiatry·K Laederach-Hofmann, B Bunzel
Jul 31, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J D Briggs
Jul 31, 2001·Transplantation·H U Meier-KriescheB Kaplan
Oct 5, 2001·Transplantation·B L Kasiske
Mar 30, 2002·Annals of Surgery·Sasan RoayaieMyron E Schwartz
Dec 4, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sasan RoayaieMyron E Schwartz
Mar 17, 2004·Transplantation·Janet A ButlerRobert C Peveler
Jun 30, 2004·Transplantation·Ergun VelidedeogluJames F Markmann
Mar 19, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Shawn J PelletierRobert M Merion
May 18, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M R K ChrisantUNKNOWN Pediatric Heart Transplant Study Group
Nov 30, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Francis Y YaoJohn P Roberts
Jul 11, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Gerd OttoMichael Pitton
Jan 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Gunda MillonigWolfgang Vogel
Jan 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Tadahiro UemuraGoran B Klintmalm
Mar 10, 2007·European Journal of Heart Failure·Andrew JabbourPeter Macdonald
Apr 27, 2007·Transplantation·Mary Amanda DewJoel B Greenhouse
Apr 28, 2007·The Annals of Thoracic Surgery·Christian D EtzChristof Schmid
Aug 19, 2007·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mark M BoucekMarshall I Hertz
Sep 1, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Timothy McCashlandThomas Faust
Dec 21, 2007·Journal of the American Society of Nephrology : JASN·Dorry L SegevRobert A Montgomery
Mar 14, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R A WolfeA B Leichtman