The Higher Frequency of Blood Group B in a Brazilian Population with HIV Infection

The Open AIDS Journal
Tor Gunnar Hugo OnstenLuciano Zubaran Goldani


To analyze the frequency of and odds for and against HIV infection based on ABO blood type in a large sample of blood donors. Coevolution between pathogens and hosts may explain the ABO system of polymorphisms. HIV-infected cells add ABO(H) blood group antigens to the viral envelope. Naturally occurring antibodies against ABO(H) antigens that are present in normal human sera are able to neutralize ABO-expressing HIV in vitro. Blood donors are ideal for studying blood groups and HIV infection in vivo because all donors are routinely typed and tested. All blood donors who donated blood between 1994 and 2010 were tested for HIV (ELISA antibody tests and Western blot test or immunofluorescence testing) and were ABO typed (direct and reverse grouping tests). HIV infection based on the ABO blood group was analyzed using the chi-square test and game theory. The total number of examined blood donors during this period was 271,410, of whom 389 were infected with HIV. B-group donors were more infected than non-B donors (p= 0.006). A more restricted antigen recognition capacity of anti-Galα1-3Gal in blood groups AB and B and a weaker antigen-binding capacity of anti-A antibodies may contribute to a higher frequency of HIV infection in blo...Continue Reading


Aug 1, 1979·Psychological Medicine·B S Everitt, A M Smith
Oct 5, 1991·BMJ : British Medical Journal·C C BlackwellD M Weir
Jul 1, 1987·Revista Da Sociedade Brasileira De Medicina Tropical·V de P TeixeiraC A de Morais
Feb 11, 2000·The Journal of Infectious Diseases·S AliN B Kiviat
Aug 6, 2004·Proceedings. Biological Sciences·Robert M SeymourKenth Gustafsson
Dec 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Chihiro KoikeMorris Goodman
Jan 24, 2007·Glycobiology·Joseph R Bishop, Pascal Gagneux
Mar 3, 2007·The Journal of Infectious Diseases·Siripen KalayanaroojGuey-Chuen Perng
Jan 17, 2008·Nature Reviews. Microbiology·Gunilla B Karlsson HedestamRichard T Wyatt
Jul 18, 2009·Molecular Immunology·Margaret E HuflejtNicolai Bovin

❮ Previous
Next ❯


Feb 24, 2016·PloS One·Modisa Sekhamo MotswalediOluwafemi Omoniyi Oguntibeju
Jun 19, 2015·Clinical Microbiology Reviews·Laura Cooling
May 28, 2019·Frontiers in Immunology·Meghan O Altman, Pascal Gagneux
Jun 29, 2021·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Didar Yanardag Acik, Mehmet Bankir

❮ Previous
Next ❯

Methods Mentioned


Software Mentioned

Statistical Package for the Social Sciences ( SPSS )

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.