PMID: 8611624Apr 10, 1996Paper

The HIR protein family: isolation and characterization of a complete murine cDNA

Biochimica Et Biophysica Acta
C ScampsM Lipinski

Abstract

A full-length cDNA has been isolated for the murine homolog of the human HIRA protein, a member of the HIR family of nuclear proteins that is encoded from the chromosome 22 region critical for the DiGeorge syndrome. This family also contains Hir1p and Hir2p, two proteins identified as regulators of histone gene transcription in yeast. The murine and human amino acid sequences are 95.3% identical, with a striking 99.2% identity in the N-terminal WD repeat domain that is characteristic of the family. The two cDNAs are highly conserved within the coding regions, but also in the entire 5' untranslated region and in a strikingly long stretch of nucleotides in the 3' untranslated region.

Citations

Aug 15, 2002·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Thomas M MaynardAnthony-Samuel LaMantia
Aug 26, 1998·Biochemical and Biophysical Research Communications·R LlevadotP Scambler
Jun 7, 2002·Molecular Cell·Dominique Ray-GalletGeneviève Almouzni
May 19, 2012·Cytoskeleton·Christian Gonzalez-BillaultAlfredo Caceres
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