The histogenesis of clear cell adenocarcinoma of the lower urinary tract. Case series and review of the literature

Human Pathology
P A DrewV O Speights

Abstract

Clear cell adenocarcinoma of the lower urinary tract is a rare neoplasm whose histogenesis has not been thoroughly investigated. We have examined six specimens of clear cell adenocarcinomas collected from three institutions using histological, histochemical, and immunohistochemical techniques. Results indicate that almost all clear cell adenocarcinomas of this region express morphological and antigenic features, suggesting müllerian differentiation, and that müllerian differentiation is not a feature of either nonclear cell adenocarcinomas or normal female paraurethral glands. Including the authors' six specimens, 46 specimens have been reported in the available English literature. The accumulated experience confirms the initial impression that these tumors develop predominantly in the urethras of women and occur over a wide age range. Despite high stage at diagnosis, most patients have been alive with no evidence of disease when reported, a prognosis that seems to apply regardless of length of follow-up.

References

Jul 1, 1977·Urology·P C CeaG F Gray
Jul 1, 1977·Urology·A B Skor, M M warren
Nov 1, 1985·The American Journal of Surgical Pathology·R H Young, R E Scully
Mar 1, 1987·Histopathology·I A KoelmaG J Fleuren
Jan 1, 1987·Ultrastructural Pathology·M T HullJ N Eble
Jan 1, 1983·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·S E KabawatR B Colvin
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·N Schnoy, W Leistenschneider
Feb 1, 1983·Journal of Surgical Oncology·M KanokogiF Ikoma
Jan 1, 1981·Scandinavian Journal of Urology and Nephrology·B M PhilipsonS Nilsson

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Citations

Jan 24, 2014·Case Reports in Pathology·Sarawut KongkarnkaSurapan Khunamornpong
Jan 16, 2007·The American Journal of the Medical Sciences·Betsy AdamsUzair B Chaudhary
Nov 8, 2011·Clinical Genitourinary Cancer·Stephen V LiuRamesh K Ramanathan
Oct 28, 2008·The Journal of Urology·Christina M Bagby, Gregory T MacLennan
Oct 1, 2008·Clinical Genitourinary Cancer·Joe Miller, R Jeffrey Karnes
Jul 25, 2009·Pathology International·Stavros I TyritzisConstantinos A Constantinides
Aug 19, 2006·Pathology·Dennis Lum
May 13, 2006·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·N KurodaE Miyazaki
Dec 6, 2000·Gynecologic Oncology·Y M ChanL C Wong
Feb 17, 2015·International Journal of Surgical Oncology·Anthony Kodzo-Grey Venyo
Jan 1, 2014·International Scholarly Research Notices·Anthony Kodzo-Grey Venyo
Jun 10, 2005·Annals of Diagnostic Pathology·Gabriela GualcoFernando Cravioto
Jul 11, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·R VangM T Deavers
Oct 7, 2000·The American Journal of Surgical Pathology·C C PanJ I Epstein
May 28, 2010·Applied Immunohistochemistry & Molecular Morphology : AIMM·Kurt B HodgesLiang Cheng
Jan 28, 2010·Journal of the Chinese Medical Association : JCMA·Chi-Min ShihChin-Chen Pan
Feb 5, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A H OrmsbyJ R Goldblum
Oct 31, 2012·Korean Journal of Pathology·Jee-Young HanSang-Min Yoon
Jan 18, 2020·Journal of Clinical Medicine·Zhengqiu ZhouRamon C Sun
Dec 12, 2003·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Atcharaporn PongtippanElvio G Silva
Aug 19, 2014·The American Journal of Surgical Pathology·Gladell P PanerGary D Steinberg
Mar 15, 2005·Scandinavian Journal of Urology and Nephrology·Mustafa Kösem, Erdal Sengül
Mar 10, 2019·BMJ Case Reports·Tamani JayawardhanaSanjeev Madaan
Mar 15, 2012·International Journal of Surgical Pathology·Borislav A Alexiev, Charles M LeVea
Jan 12, 2013·Virchows Archiv : an International Journal of Pathology·Borislav A Alexiev, Fabio Tavora
Apr 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ming-Tse SungLiang Cheng
Jan 20, 2021·International Urology and Nephrology·Erica On-Ting ChanJeremy Yuen-Chun Teoh
Jan 20, 2021·International Journal of Surgical Pathology·Carlos Padilla-AnsalaPilar González-Peramato
Apr 20, 2021·Urology Case Reports·Ali Al-GonaimSultan S Alkhateeb
Sep 16, 2008·Archives of Pathology & Laboratory Medicine·Katherine SunPamela D Unger
Jun 6, 2009·Archives of Pathology & Laboratory Medicine·Adebowale J Adeniran, Pheroze Tamboli
May 20, 2005·Pathology, Research and Practice·Rosenblat YvgeniaRumelia Koren

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