The histogram analysis of apparent diffusion coefficient in differential diagnosis of parotid tumor.

Dento Maxillo Facial Radiology
Peiqian ChenLing Zhu

Abstract

Use apparent diffusion coefficient (ADC) histogram to investigate whether the parameters of ADC histogram can distinguish between benign and malignant tumors and further differentiate the tumor subgroups. This study retrospectively enrolls 161 patients with parotid gland tumors. Histogram parameters including mean, inhomogeneity, skewness, kurtosis and 10th, 25th, 50th, 75th, 90th percentiles are derived from ADC mono-exponential model. Mann-Whitney U test is used to compare the differences between benign and malignant groups. Kruskal-Wallis test with post-hoc Dunn-Bonferroni method is used for subgroup classification, then receiver operating characteristic curve analysis is performed in mean ADC value to obtain the appropriate cutoff values. Except for kurtosis and 90th percentile, there are significant differences in all other ADC parameters between benign and malignant groups. In subgroup classification of benign tumors, there are significant differences in all ADC parameters between pleomorphic adenoma and Warthin's tumor (area under curve 0.988; sensitivity 93.8%; specificity 94.7%; all ps < 0.05). Pleomorphic adenoma has high value in mean than basal cell adenoma (area under curve 0.819; sensitivity 76.9%; specificity 76....Continue Reading

References

Nov 18, 2003·European Radiology·Stefan C A SteensMark A van Buchem
Mar 1, 2009·Head and Neck Pathology·Raja R Seethala
Dec 4, 2012·The Laryngoscope·Etienne WyssAndreas Arnold
Nov 19, 2015·Radiology·Robert J GilliesHedvig Hricak
Feb 4, 2016·Dento Maxillo Facial Radiology·Hiroki MukaiTakashi Uno
Apr 5, 2016·Otolaryngologic Clinics of North America·Babak Larian
Mar 23, 2017·Journal of Magnetic Resonance Imaging : JMRI·Chen ChuZhengyang Zhou
May 20, 2017·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Bogusław MikaszewskiCzesław Stankiewicz
Jun 24, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Miquel QuerAlfio Ferlito
Jul 14, 2017·Clinical Imaging·Eiji MatsusueToshihide Ogawa
Jul 3, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Gao MaFei-Yun Wu
Jul 5, 2018·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Wei ZhangDanke Su
Mar 30, 2019·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Ali H ElmokademTalal Amer
Apr 29, 2019·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Luciana MunhozEmiko Saito Arita

❮ Previous
Next ❯

Citations

Apr 26, 2021·International Journal of Oral and Maxillofacial Surgery·A A K Abdel RazekB Mowafey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.