The histological characteristics, age-related thickness change of skin, and expression of the HSPs in the skin during hair cycle in yak (Bos grunniens)

PloS One
X YangYun Meng

Abstract

This experiment was conducted to study the histological characteristics, age-related thickness changes, and expression of HSPs in the skin of yak. A total of 20 yaks (10 males and 10 females) were used. Different regions of the normal skin of three different ages (newborn, half-year-old and adult) of yaks were harvested for histological study and thickness measurement. Biopsy samples were taken from the scapula regions of the skin from the same five approximately 1-year-old yaks during the hair cycle (telogen, anagen and catagen). RT-PCR, western blot and immunohistochemistry methods using the mRNA and protein levels were used to detect the expression of HSP27, HSP70 and HSP90. RT-PCR method was used to detect the mRNA expression of CGI-58 and KDF1. The IPP6.0 software was used to analyze the immunohistochemistry and measure the thickness of the skin. The general histological structure of hairy yak skin was similar to other domestic mammals. The unique features included prominent cutaneous vascular plexuses, underdeveloped sweat glands, a large number of nasolabial glands in the nasolabial plate, and hair follicle groups composed of one primary follicle and several secondary follicles. The skin, epidermis and dermis thickness d...Continue Reading

References

Dec 1, 1975·The British Journal of Dermatology·S ShusterE McVitie
Jan 1, 1990·Gerontology·M C BranchetA M Robert
Nov 1, 1973·The British Journal of Dermatology·J T Whitton, J D Everall
Jun 1, 1968·Australian Journal of Biological Sciences·A G Lyne, D E Hollis
Nov 1, 1993·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·A J Nixon
Apr 1, 1995·The Journal of Investigative Dermatology·E V Maytin
Nov 1, 1994·The British Journal of Dermatology·Y TakemaG Imokawa
Nov 1, 1993·The British Veterinary Journal·S J YuB X Chen
Sep 1, 1993·The Journal of Investigative Dermatology·F TrautingerT A Luger
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·D J DixE M Eddy
Sep 1, 1996·Journal of Photochemistry and Photobiology. B, Biology·F TrautingerH Hönigsmann
Aug 1, 1997·International Journal of Dermatology·H HashizumeR Paus
Oct 10, 1998·The British Journal of Dermatology·C JantschitschF Trautinger
Apr 16, 1999·The Veterinary Journal·Y Cui, S J Yu
Sep 10, 1999·Annals of Medicine·M Jäättelä
Apr 25, 2000·Journal of Cutaneous Pathology·N WilsonL E Rhodes
Feb 22, 2001·Animal Reproduction Science·S J Yu, F D Li
Sep 5, 2001·The EMBO Journal·M ZyliczA Wawrzynow
Oct 31, 2001·Journal of Photochemistry and Photobiology. B, Biology·F Trautinger
Jan 5, 2002·Expert Opinion on Biological Therapy·Alison Maloney, Paul Workman
Jan 10, 2002·Cell Biology International·Ingela Kindas-MüggeConstanze Riedler
Jun 20, 2002·Clinical and Experimental Dermatology·S D Morris
Oct 11, 2002·Surgical and Radiologic Anatomy : SRA·Y Lee, K Hwang
Nov 20, 2003·Methods : a Companion to Methods in Enzymology·Pramod Srivastava
Sep 22, 2005·Nature Reviews. Cancer·Luke Whitesell, Susan L Lindquist
Nov 10, 2007·Veterinary Dermatology·A L MartinR L Hullinger
Sep 27, 2008·Pakistan Journal of Biological Sciences : PJBS·H R Ansari-Renani
Oct 4, 2008·The American Journal of Pathology·Masashi AkiyamaHiroshi Shimizu
Dec 26, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Nabiha YusufCraig A Elmets
Jan 15, 2010·Anatomia, histologia, embryologia·B YangR Wang
Jun 10, 2010·Nature Reviews. Molecular Cell Biology·Mikko TaipaleSusan Lindquist
Jun 29, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Bo YangRu Wang
Jul 24, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Y Y HeP Du
Sep 11, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Ben LiuSijiu Yu
Nov 18, 2010·Journal of Dermatological Science·Constanze JonakFranz Trautinger
Oct 22, 2011·Animal Reproduction Science·Fan JiangFengLiu Ben
Apr 24, 2012·The International Journal of Biochemistry & Cell Biology·Julie AcunzoPalma Rocchi
Oct 10, 2012·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Deyong DuanYan Cui
Jun 12, 2013·Cancer Letters·Leslie CalapreMel Ziman

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Citations

Aug 23, 2018·Journal of Cellular Physiology·Penggang LiuJunxing Ma
Mar 12, 2019·Animal : an International Journal of Animal Bioscience·E SaccàE Piasentier
Oct 4, 2019·Scientific Reports·Jin-Wei XinJin-Cheng Zhong
Feb 7, 2019·Journal of Cellular Physiology·Liang-Li SongJun-Feng He

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Methods Mentioned

BETA
PCR
electrophoresis

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