The history and future of melanoma staging

Journal of Surgical Oncology
John F ThompsonRichard A Scolyer

Abstract

The evolution and progressive refinement of an internationally accepted melanoma staging system over the last 50 years has resulted in much greater accuracy and increased utility, but the staging process has become more complex and less intuitive. This raises the question of whether melanoma staging should continue to develop with ever-increasing levels of complexity, or whether attempts should be made to produce an alternative system that is simpler and more intuitive. The current, TNM-based American Joint Committee on Cancer (AJCC) staging system for melanoma incorporates only some of the prognostic factors of proven significance. However, the information that is now available about these and other, well-documented prognostic factors allows accurate prediction of an individual melanoma patient's prognosis using a computer-generated estimate. Thus an alternative staging strategy that could be considered in the future would be to use such an estimate to obtain a numerical score for each patient, based on all available information agreed to be of prognostic relevance. A stage grouping could then be assigned on the basis of that score, according to previously determined score ranges for each stage and substage. The advantages of ...Continue Reading

References

Jul 30, 1979·World Journal of Surgery·A S Ketcham, W O Christopherson
Jun 15, 1990·International Journal of Cancer. Journal International Du Cancer·D M EuhusD L Morton
Oct 1, 1990·Journal of Surgical Oncology·C L SlingluffH F Seigler
Jan 1, 1989·Cancer Immunology, Immunotherapy : CII·D M EuhusD L Morton
Sep 15, 1982·International Journal of Cancer. Journal International Du Cancer·A J CochranR B Gaynor
Jul 1, 1980·The Journal of Surgical Research·N S RoteD L Morton
Aug 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A C BuzaidR S Benjamin
Aug 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D S HoonD L Morton
Dec 1, 1993·The Journal of Investigative Dermatology·P BrossartW Hunstein
May 1, 1996·Journal of the National Cancer Institute·U KunterJ Atzpodien
Jul 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B MelladoJ Estapé
Mar 1, 1996·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K PittmanP Selby
Mar 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A C BuzaidR S Benjamin
Aug 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R GläserW Tilgen
Aug 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F A JungE A Grimm
May 20, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B J CurryP Hersey
Jun 17, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J E GershenwaldM I Ross
Mar 10, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J E GershenwaldM I Ross
Aug 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G PalmieriG Castello
Oct 3, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P J BostickD S Hoon
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M DeichmannH Näher
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B J CurryP Hersey
Apr 4, 2000·Human Pathology·A J CochranR Elashoff
Nov 25, 2000·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·R A GhosseinD G Coit
Nov 25, 2000·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·B J CurryP Hersey
Aug 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C M BalchA Morabito
Aug 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C M BalchJ F Thompson
Aug 10, 2002·Seminars in Oncology·Dirk J RuiterUNKNOWN Pathology Committee of the European Organization Research and Treatment of Cancer (EORTC) Melanoma Group
Mar 1, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Giuseppe PalmieriGiuseppe Castello
Aug 19, 2003·Seminars in Surgical Oncology·Charles M BalchJohn F Thompson

❮ Previous
Next ❯

Citations

Feb 22, 2005·Lancet·John F ThompsonRichard F Kefford
May 27, 2008·Actas dermo-sifiliográficas·C MangasC Ferrándiz
Apr 16, 2009·Proceedings of the National Academy of Sciences of the United States of America·Lin Z LiJerry D Glickson
Dec 23, 2010·Future Oncology·Virginia TorresArun D Singh
Feb 18, 2012·Future Oncology·Pierre L Triozzi, Arun D Singh
Nov 30, 2010·Surgical Oncology Clinics of North America·Paxton V Dickson, Jeffrey E Gershenwald

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.