The history, genotoxicity, and carcinogenicity of carbon-based fuels and their emissions. Part 3: diesel and gasoline

Mutation Research. Reviews in Mutation Research
Larry D Claxton

Abstract

Within this review the genotoxicity of diesel and gasoline fuels and emissions is placed in an historical context. New technologies have changed the composition of transportation methods considerably, reducing emissions of many of the components of health concern. The similarity of modern diesel and gasoline fuels and emissions to other carbonaceous fuels and emissions is striking. Recently an International Agency for Research on Cancer (IARC) Working Group concluded that there was sufficient evidence in humans for the carcinogenicity of diesel exhaust (Group 1). In addition, the Working Group found that diesel exhaust has "a positive association (limited evidence) with an increased risk of bladder cancer." Like most other carbonaceous fuel emissions, diesel and gasoline exhausts contain toxic levels of respirable particles (PM <2.5μm) and polycyclic aromatic hydrocarbons. However, the level of toxic components in exhausts from diesel and gasoline emissions has declined in certain regions over time because of changes in engine design, the development of better aftertreatment devices (e.g., catalysts), increased fuel economy, changes in the fuels and additives used, and greater regulation. Additional research and better exposure...Continue Reading

References

Jul 1, 1978·Cancer Letters·Y Y WangE T Wei
Nov 1, 1979·The American Journal of Sports Medicine·J S Cox, H W Lenz
Sep 1, 1976·Journal of Toxicology and Environmental Health·L Fishbein
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J McCannB N Ames
Dec 1, 1975·Environmental Health Perspectives·C L Comar, N Nelson
Oct 1, 1992·Mutation Research·R Santos-Mello, B Cavalcante
Jan 1, 1992·International Archives of Occupational and Environmental Health·P T Scheepers, R P Bos
Jul 1, 1992·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·C LindamoodR R Maronpot
Jan 1, 1992·American Journal of Industrial Medicine·K SteenlandD Zaebst
Oct 1, 1990·Scandinavian Journal of Work, Environment & Health·P GustavssonC Hogstedt
Oct 1, 1990·Journal of the Air & Waste Management Association·R E Rasmussen
Jan 1, 1991·International Archives of Occupational and Environmental Health·M Granella, E Clonfero
Aug 1, 1991·Scandinavian Journal of Work, Environment & Health·T PartanenA Ojajärvi
Jan 1, 1990·Environmental and Molecular Mutagenesis·T E KleindienstL D Claxton
Aug 1, 1987·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·J L MauderlyR O McClellan
Apr 1, 1985·American Journal of Public Health·D Rosner, G Markowitz
Oct 1, 1989·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·R H McKee, R T Plutnick
Jan 1, 1989·American Journal of Industrial Medicine·G SteineckS E Norell
May 1, 1988·Mutagenesis·T M BrooksD H Hutson
May 1, 1988·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·J Lewtas
Jan 1, 1988·Environmental and Molecular Mutagenesis·D B McGregorW J Caspary
Apr 1, 1988·The American Review of Respiratory Disease·E GarshickF E Speizer
Jun 1, 1986·Environmental Research·J S DutcherR O McClellan
Jan 1, 1987·Environmental Mutagenesis·E ZeigerW Speck
Oct 1, 1985·Environmental Health Perspectives·P E Enterline, J Viren
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B N AmesF D Lee
Mar 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B N AmesW E Durston
Dec 1, 1973·Environmental Health Perspectives·B N Ames
Mar 1, 1982·Mutation Research·Y OhnishiK Furuya
Sep 1, 1982·Scandinavian Journal of Work, Environment & Health·K FredgaM Berlin
Jan 1, 1983·Environmental Health Perspectives·U Rannug
Jan 1, 1983·Environmental Health Perspectives·U StenbergR Westerholm

❮ Previous
Next ❯

Citations

Dec 6, 2014·Mutation Research. Reviews in Mutation Research·Larry D Claxton
Feb 19, 2016·Environmental Science & Technology·Micah N JasperHisham El-Masri
Apr 9, 2020·International Journal of Molecular Sciences·Eleonora Marta LonghinMaurizio Gualtieri
Dec 11, 2020·Journal of Hazardous Materials·Bei WangKin-Fai Ho

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Biofuels (ASM)

Biofuels are produced through contemporary processes from biomass rather than geological processes involved in fossil fuel formation. Examples include biodiesel, green diesel, biogas, etc. Discover the latest research on biofuels in this feed.

Adenoma, Liver Cell

Liver Cell Adenoma or hepatic adenoma is a rare benign tumor. It is associated with birth control use or pregnancy. Discover the latest research on Liver Cell Adenoma here.

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Related Papers

Revue des maladies respiratoires
C Habert, R Garnier
International Archives of Occupational and Environmental Health
William B BunnCharles A Lapin
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
© 2021 Meta ULC. All rights reserved