The history of antivenoms development: Beyond Calmette and Vital Brazil

Toxicon : Official Journal of the International Society on Toxinology
Carla Cristina Squaiella-BaptistãoDenise V Tambourgi

Abstract

This review presents the main contributions to our knowledge regarding the development of antivenoms for therapeutic use in victims of venomous animal bites. We cover the progress of serum therapy since tetanus and diphtheria antitoxins in Germany and France until the current scenario of antivenom production worldwide. During these more than 120 years of antivenom development, many researchers contributed to establish what are nowadays the antivenoms used for therapeutic purpose. The history of antivenoms development is fascinating! This review aims to recognize all those who contributed to the establishment of new sera, new methodologies and saving lives: much more than Calmette and Vital Brazil.

Citations

Nov 7, 2019·Frontiers in Immunology·Karen Larissa Pereira de CastroClara Guerra-Duarte
May 28, 2019·Pharmaceuticals·Isabel C Henao CastañedaLina M Preciado
Apr 2, 2020·Archives of Toxicology·Priscila Hess LopesDenise V Tambourgi
Jul 30, 2019·Frontiers in Immunology·Manuela B PuccaAndreas H Laustsen
Mar 22, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Isabel Henao CastañedaJorge Jios
Dec 11, 2020·International Immunopharmacology·Camila B P da CostaHelena C Castro
Jan 20, 2021·Toxicon : Official Journal of the International Society on Toxinology·Ana Luísa Soares de MirandaBenito Soto-Blanco
Apr 7, 2019·Toxicon : Official Journal of the International Society on Toxinology·Archana DekaRobin Doley
Jul 28, 2021·Toxicology Letters·Larissa Magalhães AlvarengaMarcel Ivan Ramírez
Jun 18, 2019·Toxicon : Official Journal of the International Society on Toxinology·Clara Guerra-DuarteCarlos Chávez-Olórtegui

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