The History of Maltose-active Disaccharidases

Journal of Pediatric Gastroenterology and Nutrition
Michael J Lentze

Abstract

The history of maltose-active disaccharidases is closely related to the history of the sugar and starch industry. It began in the 19th century, when a shortage of cane sugar occurred in continental Europe, because Napoleon Bonaparte decreed that no goods could be imported from England to the countries he occupied. Other sugar sources had to be found, and it led to the identification of sugar beets as alternative source of sugar by Marggraf in 1774, to the detection of starch hydrolysis by diluted sulfuric acid by Kirchhoff in 1812, and to the starch digestion enzyme, α-amylase, by Payen in 1833. In the 20th century, Borkström's group in Sweden investigated the absorption of nutrients in human adults by transintubation techniques and found that the luminal concentration of invertase was small compared to that of α-amylase. They speculated that the major locus of this enzyme activity must be in the intestinal cells. Borkström's coworker, Dahlqvist, investigated the maltose-active enzymes in pig intestine, and a second group around Semenza studied the maltase-active enzymes in rabbit intestine. After the first descriptions of congenital sucrase-isomaltase deficiency in 1960 and 1961, the research on disaccharidases increased. Dahl...Continue Reading

References

Dec 1, 1985·Journal of Pediatric Gastroenterology and Nutrition·A Dahlquist, G Semenza
Jan 6, 1970·Biochimica Et Biophysica Acta·R GitzelmannG Semenza
Feb 28, 1998·The Journal of Biological Chemistry·B L NicholsE Sterchi
Oct 1, 1957·The Journal of Clinical Investigation·B BORGSTROMJ SJOVALL
Aug 6, 1960·Lancet·H A WEIJERSW K DICKE
Feb 1, 1963·The Journal of Pediatrics·S AURICCHIOA PARKER
Jan 1, 1964·Analytical Biochemistry·A DAHLQVIST
Oct 1, 1964·Archives of Disease in Childhood·E A BURGESSR E TONGE

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Citations

Feb 7, 2020·Animal : an International Journal of Animal Bioscience·D L Harmon, K C Swanson
May 16, 2018·Journal of Pediatric Gastroenterology and Nutrition·Buford Nichols, William J Klish
May 8, 2021·Applied Microbiology and Biotechnology·Cecelia A Garcia, Jeffrey G Gardner

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