The human urinary microbiome and how it relates to urogynecology

International Urogynecology Journal
Jenifer SchneeweissWolfgang Umek

Abstract

Recent studies applying molecular techniques have demonstrated the presence of a urinary microbiota not detected by standard microbiological techniques. These have been found in the urine of healthy individuals and in those suffering from clinical symptoms. The present article reviews the findings of these studies to date, describing the molecular techniques, and specifically outlining any differences in microbiomes in relation to urogynecological disease. Further, the role of commensal bacteria in the lower urinary tract is considered. An extensive literature search was conducted to identify articles on the microbiome of the female urinary tract in health and disease. We searched the electronic meta-databases Ovid MEDLINE® 1946-2015 and Embase 1974-2015. The keywords "microbiome, microbiota, bacterial colonization, microbiology, commensal bacteria, and bacteriuria" were searched in combination with "lower urinary tract symptoms, urogenital symptoms, urinary tract infection, overactive bladder and urinary incontinence." A total of 426 papers were retrieved; 33 were included in this paper. The microbiome of the female lower urinary tract shows variance between individuals and between age groups. There are significant differences...Continue Reading

References

Dec 1, 1994·Scandinavian Journal of Primary Health Care·A BaerheimA Digranes
Feb 14, 2003·Lancet·Francisco Guarner, Juan-R Malagelada
Jan 4, 2006·World Journal of Urology·Gregor Reid, Andrew W Bruce
Oct 19, 2007·Nature·Peter J TurnbaughJeffrey I Gordon
Oct 13, 2009·Genome Research·UNKNOWN NIH HMP Working GroupMark Guyer
Feb 10, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J F Cryan, S M O'Mahony
Apr 19, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ann E StapletonWalter E Stamm
Jan 27, 2012·Journal of Clinical Microbiology·Alan J WolfeLinda Brubaker
Mar 27, 2012·Current Opinion in Immunology·Alexander V Chervonsky
May 4, 2012·Science Translational Medicine·Pawel GajerJacques Ravel
Jun 16, 2012·Nature·Tanya YatsunenkoJeffrey I Gordon
Sep 13, 2012·Nature Reviews. Neuroscience·John F Cryan, Timothy G Dinan
Apr 19, 2013·Journal of Clinical Microbiology·Rajvinder KhasriyaJames Malone-Lee
May 25, 2015·American Journal of Obstetrics and Gynecology·Linda Brubaker, Alan J Wolfe
Jul 27, 2015·American Journal of Obstetrics and Gynecology·Meghan M PearceUNKNOWN Pelvic Floor Disorders Network

❮ Previous
Next ❯

Citations

Oct 16, 2016·International Urogynecology Journal·Yuko M KomesuMarie Gantz
Jan 10, 2019·Climacteric : the Journal of the International Menopause Society·Carrie Jung, Linda Brubaker
Nov 2, 2019·Climacteric : the Journal of the International Menopause Society·E RussoT Simoncini
Mar 23, 2017·International Urogynecology Journal·Vatché A MinassianWalter F Stewart
Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Christina M Coleman, Daneel Ferreira
Dec 13, 2016·International Urogynecology Journal·Maurizio SeratiUNKNOWN Publication Committee of the Italian Society of Urodynamics
Jun 19, 2020·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Riccardo LombardoCosimo De Nunzio
Jan 28, 2021·Scientific Reports·Nadia AmmitzbøllSuzette Sørensen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
G Amarenco
JAMA : the Journal of the American Medical Association
James G Young, Kesavapilla Subramonian
JAMA : the Journal of the American Medical Association
Toby C Chai
JAMA : the Journal of the American Medical Association
William Andrew Bell, Naseem Amarshi
© 2021 Meta ULC. All rights reserved