The Hyperactivity of Efferent Auditory System in Patients with Schizophrenia: A Transient Evoked Otoacoustic Emissions Study

Psychiatry Investigation
Noor Alaudin Abdul WahabMohd Normani Zakaria

Abstract

Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory pathway on cochlear outer hair cells among schizophrenia patients are limited. The present, case-control, study examined the contralateral suppression of transient evoked otoacoustic emissions (TEOAEs) in patients with schizophrenia. Participants were twenty-three healthy controls and sixteen schizophrenia patients with normal hearing, middle ear and cochlear outer hair cells function. Absolute non-linear and linear TEOAEs were measured in both ears by delivering clicks stimuli at 80 dB SPL and 60 dB SPL respectively. Subsequently, contralateral suppression was determined by subtracting the absolute TEOAEs response obtained at 60 dBpe SPL during the absence and presence of contralateral white noise delivered at 65 dB HL. No attention tasks were conducted during measurements. We found no significant difference in absolute TEOAEs responses at 80 dB SPL, in either diagnosis or ear groups (p>0.05). However, the overall contralateral suppression was significantly larger in schizophrenia patients (p<0.05). Sp...Continue Reading

References

Aug 1, 1994·British Journal of Audiology·D PrasherL Luxon
Feb 20, 1999·Archives of General Psychiatry·J S KwonM E Shenton
Nov 14, 2000·Archives of General Psychiatry·S S ShergillP K McGuire
Dec 16, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·E VeuilletL Collet
May 12, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·G De CeulaerP J Govaerts
Feb 19, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Junji IchikawaHerbert Y Meltzer
Nov 14, 2003·Schizophrenia Research·André AlemanRené S Kahn
May 27, 2005·PLoS Medicine·Dinesh Bhugra
Jun 14, 2005·The Journal of Laryngology and Otology·Eui-Cheol Nam
Sep 3, 2005·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Judith M Ford, Daniel H Mathalon
Sep 10, 2005·Cerebral Cortex·Xavier PerrotLionel Collet
Oct 4, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Stefan LeuchtRolf Engel
Aug 28, 2007·Psychiatry Research·Owen G O'DalySukhwinder S Shergill
Jun 3, 2008·European Psychiatry : the Journal of the Association of European Psychiatrists·N E M van HarenR S Kahn
Sep 6, 2008·The International Journal of Neuropsychopharmacology·Risto Näätänen, Seppo Kähkönen
Sep 19, 2008·Schizophrenia Research·Matcheri S KeshavanHenry A Nasrallah
Jan 20, 2009·International Journal of Pediatric Otorhinolaryngology·Aslihan Kulekci UgurNebil Goksu
Jul 25, 2009·Clinical Pharmacology and Therapeutics·Z J Daskalakis, T P George
Oct 23, 2009·Biological Psychiatry·Claudia J P SimonsSukhwinder S Shergill
Mar 31, 2010·Brain : a Journal of Neurology·Faranak FarzanZafiris J Daskalakis
Aug 24, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Naoki GotoJun Nakamura
Oct 22, 2010·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Leontien I GevenPim van Dijk
Oct 6, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Ralph E HoffmanMichelle Hampson
Mar 1, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Gemma ModinosPaul Allen
Mar 7, 2012·Brazilian Journal of Otorhinolaryngology·Daila Urnau, Tania Maria Tochetto
Oct 18, 2012·Journal of the American Academy of Audiology·Andrew Stuart, Alyson K Butler
Jul 5, 2013·American Journal of Audiology·Vasiliki Vivian IliadouApostolos Iacovides
Sep 27, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carolina WedemeyerEleonora Katz
Jan 15, 2015·Pharmacology & Therapeutics·William T O'Connor, Sean D O'Shea

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Citations

Jun 27, 2018·Wiley Interdisciplinary Reviews. Developmental Biology·Michelle M Frank, Lisa V Goodrich
Dec 7, 2017·Psychiatry Investigation·Noor Alaudin Abdul WahabSuzaily Wahab
Jun 2, 2021·Journal of the American Academy of Audiology·Frank E MusiekAlyssa J Davidson

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