The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length

Molecular Biology of the Cell
Emily L HunterWinfield S Sale

Abstract

We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.

References

Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·K L Kindle
Nov 1, 1987·The Journal of Cell Biology·S M Pasquale, U W Goodenough
Jan 1, 1986·Methods in Enzymology·G B Witman
Jan 1, 1995·Methods in Cell Biology·P A Lefebvre
Jan 1, 1995·Methods in Cell Biology·S K Dutcher
Jan 1, 1996·Journal of Structural Biology·J R KremerJ R McIntosh
Jul 21, 2004·Journal of Computational Chemistry·Eric F PettersenThomas E Ferrin
Oct 8, 2004·Molecular Biology of the Cell·Triscia W HendricksonWinfield S Sale
Jul 7, 2005·The Journal of Cell Biology·Gregory J PazourGeorge B Witman
Sep 27, 2005·Journal of Structural Biology·David N Mastronarde
Aug 19, 2006·Science·Daniela NicastroJ Richard McIntosh
Apr 5, 2007·Nature Protocols·Cristina V IancuGrant J Jensen
Jun 6, 2007·Cell Motility and the Cytoskeleton·Maureen WirschellWinfield S Sale
Dec 25, 2007·Cell Motility and the Cytoskeleton·Maureen WirschellWinfield S Sale
Dec 17, 2009·The Journal of Cell Biology·Thomas HeuserDaniela Nicastro
Jan 1, 2009·Methods in Cell Biology·Carlo IominiSusan K Dutcher
May 28, 2011·Journal of Structural Biology·John M HeumannDavid N Mastronarde
Sep 20, 2011·Proceedings of the American Thoracic Society·Lawrence E OstrowskiCecilia W Lo
Dec 14, 2011·Differentiation; Research in Biological Diversity·Daisuke Kobayashi, Hiroyuki Takeda
Jun 27, 2012·Proceedings of the National Academy of Sciences of the United States of America·Thomas HeuserDaniela Nicastro
Mar 19, 2013·Methods in Enzymology·Karl F Lechtreck
Jun 14, 2013·Molecular Biology of the Cell·Stephanie A ZlaticVictor Faundez
Dec 10, 2013·Current Biology : CB·Kathryne N WrenKarl F Lechtreck
Mar 13, 2014·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Sagar BhogarajuEsben Lorentzen
Jul 1, 2014·Proceedings of the National Academy of Sciences of the United States of America·Mikito OwaKen-ichi Wakabayashi
Nov 21, 2014·Molecular Biology of the Cell·Toshiyuki OdaMasahide Kikkawa
Jan 15, 2015·The Journal of Cell Biology·Julie M CraftKarl F Lechtreck
Jun 13, 2015·Molecular Biology of the Cell·Junya AwataGeorge B Witman
Oct 27, 2015·Trends in Biochemical Sciences·Karl F Lechtreck
Apr 14, 2016·Journal of Cell Science·Tomohiro KuboGeorge B Witman

❮ Previous
Next ❯

Citations

Oct 27, 2018·Microscopy·Tomohiro Kubo, Toshiyuki Oda
Apr 11, 2019·Soft Matter·Minji KimJ Mark Meacham
Apr 6, 2019·American Journal of Respiratory Cell and Molecular Biology·Amjad Horani, Steven L Brody
Dec 31, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Susan K Dutcher
Mar 10, 2020·FEMS Microbiology Reviews·Morgan BeebyDavid R Mitchell
Apr 6, 2019·Nature Reviews. Molecular Cell Biology·Maxence V Nachury, David U Mick
May 28, 2020·Critical Reviews in Biochemistry and Molecular Biology·Kazuhisa Nakayama, Yohei Katoh
May 17, 2019·The Journal of Cell Biology·Lei ZhaoGeorge B Witman
Jun 18, 2021·Journal of Cell Science·Mareike A Jordan, Gaia Pigino
May 17, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Gang FuDaniela Nicastro

❮ Previous
Next ❯

Datasets Mentioned

BETA
SRX525037

Methods Mentioned

BETA
electron microscopy
fluorescence microscopy
pull down
pull downs
pull-down
PCR
PCA
immunoprecipitation

Software Mentioned

Illustrator
PEET
Graphpad
SerialEM
Elements Advanced Research
Adobe
IMOD
NIS
UCSF Chimera
ImageJ

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.