PMID: 7993373Jun 1, 1994Paper

The identification of nuclear and mitochondrial genes by sequencing randomly chosen clones from a marsupial mammary gland cDNA library

Biochemical Genetics
C Collet, R Joseph


To increase the number of genes that can be mapped to the genome of the tammar wallaby (Macropus eugenii), we sequenced 100 randomly chosen clones from a mammary gland cDNA library. Provisional identifications were made of seven nuclear genes and one mitochondrial gene encoding two caseins, beta-galactosidase, acetyl-coenzyme A synthetase, lipoprotein lipase, inorganic pyrophosphatase, an ATP-dependent RNA helicase, and cytochrome c oxidase I. Highly conserved genes, such as that encoding acetyl-coenzyme A synthetase, were easily identified even from cross-kingdom matches. Genes which are highly divergent, however, such as those encoding the mature casein peptides, could not be aligned with homologues in the databases. Even in an organ where there is high mRNA species redundancy, the sequence characterization of expressed sequence tags provides a rapid means of gene identification for mapping purposes.


Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
May 1, 1992·Nature Genetics·R WaterstonN Halloran
Feb 13, 1992·Nature·M D AdamsJ C Venter
Feb 1, 1991·Journal of Molecular Endocrinology·C ColletK Nicholas
Jan 1, 1990·Reproduction, Fertility, and Development·C ColletK Nicholas
Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Nov 15, 1989·Biochemical and Biophysical Research Communications·C ColletK Nicholas
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W R Pearson, D J Lipman
Aug 1, 1987·The Journal of Dairy Research·J Bonsing, A G Mackinlay
Nov 1, 1993·The Journal of Heredity·G L WoodleeD W Cooper
Jan 1, 1993·Immunogenetics·M A GroenenM J Giphart
Jan 30, 1993·Gene·M A GroenenJ J van der Poel
Apr 7, 1993·Biochimica Et Biophysica Acta·C Collet, R Joseph

❮ Previous
Next ❯


Apr 1, 1997·Mammalian Genome : Official Journal of the International Mammalian Genome Society·G Tosser-KloppF Hatey
Dec 1, 1994·Current Opinion in Biotechnology·C Fields
Dec 11, 1999·Nucleic Acids Research·J QuackenbushJ Upton
Mar 1, 1996·Journal of Child Psychology and Psychiatry, and Allied Disciplines·E SimonoffM Rutter
Aug 10, 2000·Psychological Reports·M A Verdugo

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Mammalian Genome : Official Journal of the International Mammalian Genome Society
S A Camper, M H Meisler
The Journal of Steroid Biochemistry and Molecular Biology
M Raikhinstein, I Hanukoglu
The Journal of Steroid Biochemistry and Molecular Biology
F HateyF Gasser
© 2021 Meta ULC. All rights reserved