The Iml3 protein of the budding yeast is required for the prevention of precocious sister chromatid separation in meiosis I and for sister chromatid disjunction in meiosis II

Current Genetics
Santanu Kumar GhoshP Sinha

Abstract

The mitotic kinetochore of the budding yeast contains a number of proteins which are required for chromosome transmission but are non-essential for vegetative growth. We show that one such protein, Iml3, is essential for meiosis, in that the absence of this protein results in reduced spore viability, precocious sister chromatid segregation of artificial and natural chromosomes in meiosis I and chromosome non-disjunction in meiosis II.

Citations

Apr 18, 2012·PloS One·Yee-Fun SuJaulang Hwang
Jul 8, 2014·Cell·Julian StingeleStefan Jentsch
Nov 9, 2004·Current Biology : CB·Chad G PearsonKerry Bloom
Dec 7, 2013·Biochemical and Biophysical Research Communications·Jae Sung SeoCheol Yong Choi
Jul 15, 2015·Molecular Biology of the Cell·Régis E MeyerDean S Dawson
Jan 10, 2016·G3 : Genes - Genomes - Genetics·Daniel B Chu, Sean M Burgess
Nov 30, 2021·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Gunjan MehtaSantanu K Ghosh

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