The immediate and delayed effects of marathon running on renal function

The Journal of Urology
R A IrvingR Van Zyl-Smit

Abstract

Daily blood and 24-hour urine samples from 6 runners were studied for 2 days before and for 5 days after a 42.2 km. marathon footrace run in cool environmental conditions. Although the race caused muscle damage as shown by the increased post-race serum creatine kinase activity and C-reactive protein levels, renal function measured by urine flow rates, creatinine clearance and protein excretion was normal during the race. Sodium and fractional sodium excretion decreased during the race despite a maintained osmolar clearance, and remained low for the next 48 hours, whereas osmolar clearance decreased sharply for the remainder of the race day but it was significantly elevated on days 2 to 4 after the race. Creatinine clearance was increased significantly 24 hours after the race, and reached its peak 3 days after the race, while urine flow rates were elevated from days 2 to 5 after the race. Urea excretion was significantly decreased 3 to 5 days after the race, while creatinine excretion was increased significantly on day 3 after the race. Glomerular proteinuria occurred 24 hours after the race with no associated reduction in tubular reabsorption of the low molecular weight protein beta-2-microglobulin. This study shows previously ...Continue Reading

References

Jun 1, 1978·European Journal of Clinical Investigation·J R Poortmans, B Vancalck
Jan 1, 1977·Annals of the New York Academy of Sciences·D L Costill
Apr 1, 1979·Clinical Science·E S WilliamsM L Forsling
Jan 1, 1979·Nephron·E T MacSearraighH B Schiff
Feb 1, 1978·Scandinavian Journal of Clinical and Laboratory Investigation·H E Refsum, S B Strømme
May 10, 1977·European Journal of Applied Physiology and Occupational Physiology·M B MaronJ E Wilkerson
Jul 1, 1976·Journal of Applied Physiology·K J Kosunen, A J Pakarinen
Jan 1, 1973·Nephron·L WibellI Berggård
Sep 1, 1974·Annals of Internal Medicine·J P KnochelR J Hamburger
Jun 1, 1967·Acta Physiologica Scandinavica·J CastenforsM Piscator
Jan 20, 1983·The New England Journal of Medicine·H GrafR Prager
Dec 1, 1983·The American Journal of Medicine·J P BoschS Glabman
May 1, 1983·Journal of the Neurological Sciences·R S HikidaD L Costill
May 1, 1980·Urology·M BoileauC V Hodges
Dec 1, 1981·Southern Medical Journal·J A Neviackas, J H Bauer
Apr 1, 1980·The Physician and Sportsmedicine·P J Stewart, G A Posen

❮ Previous
Next ❯

Citations

Sep 1, 1992·International Journal of Sport Nutrition·T D Noakes
Jul 11, 2007·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Stephen A Reid, M Jonathan King
Dec 21, 2017·BMJ Open Sport & Exercise Medicine·L E HodgsonL G Forni
Dec 29, 2017·Journal of Strength and Conditioning Research·Wojciech WołyniecMarcin Renke
May 16, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sergio Luis-LimaEsteban Porrini
Jun 13, 2020·The Physician and Sportsmedicine·Morteza KhodaeeMartin D Hoffman
Jan 1, 1991·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·A S Woolf, L G Fine
May 17, 2012·Sports Medicine·Erin J HowdenJeff S Coombes
Jul 11, 2019·Praxis·Beat KnechtlePantelis T Nikolaidis
Jul 23, 2003·Journal of Applied Physiology·Filiz GündüzUmit Kemal Sentürk
Nov 4, 2004·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Stephen A ReidChris Milne
Mar 29, 2014·Anais Da Academia Brasileira De Ciências·Enrico F PugginaValdir J Barbanti
Sep 1, 1988·The Physician and Sportsmedicine·R C SandellT D Noakes
Sep 1, 1988·The Physician and Sportsmedicine·T D Nookes
Nov 22, 2017·International Journal of Occupational Safety and Ergonomics : JOSE·Nobuo Yasuda, Brent C Ruby
Oct 30, 2015·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Grant S LipmanColin Little
Aug 23, 2020·International Journal of Environmental Research and Public Health·Raffaela PeroOlga Scudiero
Mar 12, 2009·Current Sports Medicine Reports·Joseph J Bernard
Mar 24, 2011·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Beat KnechtleOliver Senn
Dec 7, 2018·Nature Reviews. Nephrology·Esteban PorriniGiuseppe Remuzzi
Dec 21, 2006·Nephron. Physiology·Umit Kemal SentürkFiliz Gündüz
Mar 4, 2014·Advances in Physiology Education·Michael B Maron
Mar 1, 1991·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·A N KhalafK G Petersen
Sep 26, 2020·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Daniel FitzpatrickLuke Hodgson
Dec 12, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Timothy W Meyer, Thomas H Hostetter

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