The immunological and metabolic responses to exercise of varying intensities in normoxic and hypoxic environments

Journal of Strength and Conditioning Research
Mark BlegenEllen Glickman

Abstract

The purpose of this study was to determine the effects of varying intensities of exercise in normoxic and hypoxic environments on selected immune regulation and metabolic responses. Using a within-subjects design, subjects performed maximal tests on a cycle ergometer in both normoxic (PiO2 = 20.94%) and hypoxic (PiO2 = 14.65%) environments to determine [latin capital V with dot above]O2max. On separate occasions, subjects then performed four randomly assigned, 1-hour exercise bouts on a cycle ergometer (two each in normoxic and hypoxic environments). The hypoxic environment was created by reducing the O2 concentration of inspired air using a commercially available hypoxic chamber. The intensities for the exercise bouts were predetermined as 40 and 60% of their normoxic [latin capital V with dot above]O2max for the normoxic exercise bouts and as 40 and 60% of their hypoxic [latin capital V with dot above]O2max for the hypoxic exercise bouts. Blood samples were collected preexercise, postexercise, 15 minutes postexercise, 2 hours postexercise, and 24 hours postexercise for the determination of interleukin-1 (IL-1), tumor necrosis factor-[alpha] (TNF-[alpha]), glucose, glycerol, free fatty acids, epinephrine, norepinephrine, and c...Continue Reading

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Citations

Apr 12, 2016·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·S A SantosR V T Dos Santos
May 22, 2013·Mediators of Inflammation·Valdir de Aquino LemosMarco Tulio de Mello
Nov 10, 2016·Nutrients·Aline Venticinque CarisRonaldo Vagner Thomatieli Dos Santos
Jul 17, 2019·The Clinical Respiratory Journal·Samile A SantosRonaldo V Thomatieli-Santos

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