Jan 1, 1992

The immunological aspect of the processes of adaptation and compensation in the acute period of craniocerebral trauma

Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
V I Gorbunov

Abstract

The dynamics of immunological values were studied in 350 patients with various types of craniocerebral trauma (CCT) in the acute period. It was established that immunological responses occur in all types of CCT. In mild CCT they are of a compensatory character. In severe trauma of the skull and brain the mechanisms of immunological protection are usually disrupted and secondary purulent complications and autoimmune processes develop. Under conditions of preliminary neurosensitization, the mechanisms of adaptation are disrupted even in mild traumas of the brain, autoimmune processes develop, which leads to a progredient course of CCT. Application of immunocorrective measures in disruption of adaptation processes improves the outcomes of CCT.

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Mentioned in this Paper

Mild Traumatic Brain Injury
Brain
Acute Disease
Antibody Formation
Concussion, Severe
Autoimmune Diseases
Bone Structure of Cranium
Autoimmune Reaction
Craniocerebral Trauma
Cellular Immune Response

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