The immunological capacity in the larvae of Pacific oyster Crassostrea gigas

Fish & Shellfish Immunology
Xiaorui SongLinsheng Song

Abstract

As the immune system has not fully developed during early developmental stages, bivalve larvae are more susceptible for pathogens, which frequently leads to the significant mortality in hatcheries. In the present study, the development of immune system and its response against bacteria challenge were investigated in order to characterize the repertoire of immunological capacity of Pacific oyster Crassostrea gigas during the ontogenesis. The phagocytosis was firstly observed in the early D-veliger larvae (17 hpf), especially in their velum site, which indicated the appearance of functional hemocytes during early D-veliger larvae stage. The whole-mount immunofluorescence assay of three pattern recognition receptors (integrin β-1, caspase-3 and C-type lectin 3) and one immune effector gene (IL17-5) was performed in blastula, early D-veliger and umbo larvae, suggested that velum and digestive gland were the potential sites of immune system in the larvae. The lowest activities of antioxidant enzymes (superoxide dismutase and catalase) and hydrolytic enzyme (lysozyme), as well as descended expression levels of 12 immune genes at the transition between embryogenesis and planktonic, indicated that the larvae at hatching (9 hpf) were in...Continue Reading

References

Nov 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·T C Cheng, G E Rodrick
Jan 1, 1989·Cold Spring Harbor Symposia on Quantitative Biology·C A Janeway
May 23, 1998·Annual Review of Immunology·S GhoshE B Kopp
Apr 14, 1999·Cell Death and Differentiation·A G Porter, R U Jänicke
Jan 19, 2002·Differentiation; Research in Biological Diversity·N Fossett, R A Schulz
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Feb 28, 2002·Annual Review of Immunology·Charles A Janeway, Ruslan Medzhitov
Jul 12, 2002·Microscopy Research and Technique·Laura CanesiCarla Pruzzo
Mar 1, 1995·Trends in Cell Biology·S C Silverstein
Apr 28, 2004·Diseases of Aquatic Organisms·Robyn M EstesRussell P Herwig
May 5, 2004·Fish & Shellfish Immunology·Antonio Luna-GonzálezMiguel Robles-Mungaray
Jun 29, 2004·PLoS Biology·Edan Foley, Patrick H O'Farrell
Nov 1, 2005·Biochemical and Biophysical Research Communications·Marcelo GonzalezEvelyne Bachère
Dec 13, 2005·The FEBS Journal·Alex N Zelensky, Jill E Gready
Feb 25, 2006·Cell·Shizuo AkiraOsamu Takeuchi
Sep 12, 2006·Developmental and Comparative Immunology·M GonzalezE Bachère
Mar 6, 2007·Developmental and Comparative Immunology·Ana TirapéViviane Boulo
Jun 15, 2007·Developmental and Comparative Immunology·Xunhao XiongRongqing Zhang
Apr 9, 2008·Developmental and Comparative Immunology·Steven RobertsFrederick Goetz
Feb 12, 2009·Development, Growth & Differentiation·Vyacheslav Dyachuk, Nelly Odintsova
Jan 5, 2011·Fish & Shellfish Immunology·Linlin ZhangGuofan Zhang
May 11, 2011·Evidence-based Medicine·Michel de Lorgeril
May 27, 2014·Developmental and Comparative Immunology·Lingling WangLinsheng Song

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Citations

Aug 4, 2016·Developmental and Comparative Immunology·Vyacheslav A Dyachuk
Oct 4, 2016·Developmental and Comparative Immunology·Weilin WangLinsheng Song
Apr 10, 2020·Scientific Reports·Emma Timmins-SchiffmanSteven B Roberts
Jun 27, 2020·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Anna V IvaninaInna M Sokolova
Jun 8, 2021·Developmental and Comparative Immunology·Ying SongLinsheng Song

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