PMID: 6976060Jul 1, 1981Paper

The immunological status of children with atopic dermatitis

Acta paediatrica Scandinavica
L J BeardT W Turner

Abstract

We studied 16 children during the quiescent phase of atopic dermatitis with a broad range of in vitro immunological tests. Subnormal levels of IgA were present in 2 children, and subnormal IgG in 1. IgE levels were elevated in 6 children. T cell percentages were significantly but slightly reduced. Normal results were obtained for lymphocyte transformation to 3 mitogens, neutrophil chemotaxis, quantitative iodination and microbicidal activity, and for the serum levels of CH50, C3 and C4. Thus most of the abnormal immunological findings in atopic dermatitis nay be secondary to the disease process itself.

References

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Citations

Jul 1, 1982·Archives of Disease in Childhood·R C Cohen, A Ferrante
May 1, 1987·The British Journal of Dermatology·F ChiarelliG Morgese

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Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.