The impact of aborted radical hysterectomy in patients with cervical carcinoma

Gynecologic Oncology
Charles A LeathR D Alvarez

Abstract

To determine the impact of an aborted radical hysterectomy on morbidity and overall survival in patients undergoing surgical treatment for early stage cervical carcinoma. Following IRB approval, a computerized database identified 304 women treated with radical surgery for early stage cervical carcinoma from 1994 to 2000 of which 23 (8%) had an aborted radical hysterectomy. Of the 23 patients, 17 patients had a IB(1) lesion, 4 patients had a IB(2) lesion, and 2 patients had a IIA lesion. Median age was 42 years (range 28-60). Twenty-one patients had squamous cell carcinoma and two patients had adenocarcinoma. Radical hysterectomy was aborted for the following reasons: 11 patients had pelvic extension, seven had positive pelvic nodes, and five patients had positive paraaortic nodes. All 23 patients received postoperative radiation therapy; additionally, 12 patients received concurrent chemotherapy consisting of platinum with or without 5-FU. There were four operative complications (17%) including deep vein thrombosis, wound infection, blood transfusion, and an ileus. Four patients (17%) had radiation-associated complications. Six of 23 (26%) patients experienced a recurrence. The 5-year overall survival was 83% with a median foll...Continue Reading

References

Dec 1, 1976·American Journal of Obstetrics and Gynecology·G W Morley, J C Seski
Nov 19, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·G L BremerJ de Haan
Nov 1, 1989·International Journal of Radiation Oncology, Biology, Physics·R A PotishL B Twiggs
Mar 5, 1998·International Journal of Radiation Oncology, Biology, Physics·A H RussellJ S Chimiel
Apr 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W A PetersD S Alberts
Dec 6, 2000·Gynecologic Oncology·C W Whitney, F B Stehman
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patricia J EifelDavid G Mutch

❮ Previous
Next ❯

Citations

May 11, 2010·Obstetrics and Gynecology International·Heidi J GrayBarbara A Goff
May 12, 2007·Gynecologic Oncology·Kellie S MatthewsJ Michael Straughn
Apr 25, 2014·Journal of Gynecologic Oncology·Kanyarat KatanyooBusaba Supawattanabodee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.