Abstract
Attention deficit hyperactive disorder (ADHD) is prevalent in 5.9-7.1% of children and adolescents, and 5% of adults. It results in poor academic, occupational, and social functioning. Pharmacotherapy improves core symptoms; however, average adherence levels are low and decrease at 16-17 years of age, just before the recruitment age to Israel Defense Forces (IDF). This study evaluated the effect of adherence to ADHD pharmacotherapy on occupational performance among soldiers. Retrospective data were collected for the study cohort, which included all soldiers serving in the IDF from 2008 through 2012 (n > 500,000). Each soldier in the cohort was categorized based on adherence to treatment, as measured by prescriptions filled monthly: (1) no treatment, (2) low adherence (<2/year), (3) medium adherence (2-6/year), and (4) high adherence (>6/year). Occupational performance was evaluated by 3 indicative parameters: (1) number of sick days, (2) number of exemptions from daily activities, and (3) military profession disqualification, including sub-analysis to military profession groups. ADHD pharmacotherapy adherence correlated inversely with occupational performance, as exhibited by more sick days and exemptions from daily activities....Continue Reading
References
Jan 20, 2005·The Annals of Pharmacotherapy·Rachel A ElliottRob Horne
Aug 5, 2005·The New England Journal of Medicine·Lars Osterberg, Terrence Blaschke
Mar 9, 2006·European Child & Adolescent Psychiatry·Philip HazellDavid Michelson
Jan 24, 2007·Journal of Attention Disorders·Steven A SafrenSusan Sprich
Apr 20, 2007·Journal of Pediatric Psychology·Amanda L ThompsonElizabeth M Gnagy
Mar 4, 2008·The Journal of Clinical Psychiatry·Susan Shur-Fen GauYu-Shu Huang
Mar 25, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·Elizabeth PappadopulosJeffrey H Newcorn
May 7, 2009·Journal of Clinical Psychology in Medical Settings·Amori Yee MikamiRoger Burket
Jan 29, 2010·Postgraduate Medicine·Lisa D Adler, Andrew A Nierenberg
Jul 27, 2010·Journal of Psychiatric Research·Joseph BiedermanStephen V Faraone
Sep 24, 2010·Postgraduate Medicine·Timothy E Wilens, Thomas J Spencer
Oct 19, 2011·Current Medical Research and Opinion·Jamie C BarnerAbiola Oladapo
Jun 21, 2012·CNS Drugs·Eric Q WuM Haim Erder
Sep 6, 2012·BMC Medicine·Monica ShawL Eugene Arnold
Sep 15, 2012·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Erik G Willcutt
May 29, 2013·Current Psychiatry Reports·Alice Charach, Rebeca Fernandez
Jun 9, 2016·Journal of Attention Disorders·Eyal FruchterMark Weiser