The impact of Aeromonas salmonicida infection on innate immune parameters of Atlantic salmon (Salmo salar L)

Fish & Shellfish Immunology
Yishuai DuYing Liu

Abstract

Enzyme activities and gene expression of a number of innate immune parameters in the serum, mucus and skin of Atlantic salmon (Salmo salar) were investigated after challenge with a pathogenic strain of Aeromonas salmonicida (A. salmonicida). Fish were injected in the dorsal muscle with either 100 μl bacterium solution, about 3.05 × 10(7) CFU/ml A. salmonicida, or 100 μl 0.9% NaCl (as control group) and tissue samples were collected at days 0, 2, 4 and 6 post-injection. Lysozyme (LSZ) and alkaline phosphatase (AKP) activities in serum, mucus and skin, and LSZ and AKP mRNA expression in skin of the challenged fish were higher than those of the control at most of the experimental time, with significant differences at several time points (P < 0.05), indicating the involvement of LSZ and AKP in the innate immunity of Atlantic salmon to A. salmonicida. Superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities in mucus and skin, along with the SOD, POD and CAT mRNA expression in skin significantly decreased at day 4 and 6, indicating the decreased antioxidant capacity of the challenged fish. Glutamate pyruvate transaminase (GPT) and glutamic oxalacetic transaminase (GOT) activities in serum, mucus and skin of the chal...Continue Reading

References

Nov 1, 1971·Analytical Biochemistry·C Beauchamp, I Fridovich
Jul 1, 1993·Developmental and Comparative Immunology·J H RomboutA J Taverne-Thiele
Oct 17, 2001·Developmental and Comparative Immunology·A E Ellis
Jun 5, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·M D FastN W Ross
Jul 16, 2002·International Journal for Parasitology·Alejandro Castellanos-GonzálezAbraham Landa
Jun 14, 2005·Fish & Shellfish Immunology·Bergljót Magnadóttir
Sep 24, 2005·The FEBS Journal·Gudmundur BergssonGudmundur Hrafn Gudmundsson
Aug 1, 1997·Tissue & Cell·Y Iger, M Abraham
Oct 28, 2008·Fish & Shellfish Immunology·Chang-Che LiJiann-Chu Chen
Jan 13, 2010·Clinical Microbiology Reviews·J Michael Janda, Sharon L Abbott
Dec 24, 2013·Biologicals : Journal of the International Association of Biological Standardization·Anne Berit RomstadØystein Evensen
Apr 17, 2014·Developmental and Comparative Immunology·Marianne ArnemoTor Gjøen

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Citations

Oct 23, 2016·Fish & Shellfish Immunology·Héctor CorderoM Ángeles Esteban
Jan 1, 2021·Journal of Applied Microbiology·G Bandeira Junior, B Baldisserotto

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