The impact of aging and habitual physical activity on static respiratory work at rest and during exercise

American Journal of Physiology. Lung Cellular and Molecular Physiology
Rungchai ChaunchaiyakulNigel A S Taylor

Abstract

We investigated the effects of aging on the elastic properties of lung tissue and the chest wall, simultaneously quantifying the contribution of each component to static inspiratory muscle work in resting and exercising adults. We further evaluated the interaction of aging and habitual physical activity on respiratory mechanics. Static lung volumes and elastic properties of the lung and chest wall (pressure-volume relaxation maneuvers) in 29 chronically sedentary and 29 habitually active subjects, grouped by age, were investigated: young (Y, 20-30 years), middle-aged (M, 40-50 years), and older (O, >60 years). Using static pressure-volume data, we computed the elastic work of breathing (joules per liter, J.l(-1)), including inspiratory muscle work, over resting and exercising tidal volume excursions. Elastic work of the lung (Y = 0.79 +/- 0.05; M = 0.47 +/- 0.05; O = 0.43 +/- 0.05 J.l(-1)) and chest wall (Y = -0.49 +/- 0.06; M = -0.12 +/- 0.07; O = 0.04 +/- 0.05 J.l(-1) ) changed significantly with age (P < 0.05). With aging, a parallel displacement of the chest wall pressure-volume curve resulted in a shift from energy being stored primarily during expiration to energy storage during inspiration, and driving expiration, both a...Continue Reading

References

Jul 1, 1976·British Journal of Diseases of the Chest·G J Gibson, N B Pride
Aug 1, 1976·Journal of Applied Physiology·F R BodeP T Macklem
Oct 1, 1976·Journal of Applied Physiology·D E Leith, M Bradley
Dec 1, 1975·Journal of Applied Physiology·D E NiewoehnerL Liotta
Jan 1, 1991·European Journal of Applied Physiology and Occupational Physiology·N A Taylor, J B Morrison
Feb 1, 1991·Journal of Applied Physiology·T G Babb, J R Rodarte
Jan 1, 1990·Computers in Biology and Medicine·N A Taylor
Feb 1, 1989·Journal of Applied Physiology·H I Chen, C S Kuo
Mar 1, 1988·Journal of Applied Physiology·M J Belman, G A Gaesser
Sep 1, 1988·Journal of Applied Physiology·J L Fleg, E G Lakatta
Jul 1, 1988·Journal of Applied Physiology·J M HagbergD R Seals
Jul 1, 1986·Journal of Applied Physiology·A A Vandervoort, A J McComas
Jan 1, 1987·Journal of Applied Physiology·T L ClantonJ E Gadek
Nov 1, 1986·Journal of Applied Physiology·A J ThomasS G Kelsen
Dec 1, 1985·Journal of Applied Physiology·M EstenneA De Troyer
Apr 1, 1970·Journal of Applied Physiology·G Rizzato, L Marazzini
Dec 1, 1968·Journal of Applied Physiology·J M TurnerM E Wohl
Dec 1, 1984·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·M Younes, G Kivinen
Sep 1, 1980·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·D G StubbingN L Jones
Jan 1, 1995·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·S TeramotoH Orimo
Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·P L EnrightR E Hyatt
May 1, 1997·American Journal of Respiratory and Critical Care Medicine·M I PolkeyJ Moxham
Oct 12, 1999·Journal of Applied Physiology·N A Taylor, J B Morrison
May 8, 2000·Journal of Applied Physiology·D E O'DonnellK A Webb
Jul 1, 1954·Physiological Reviews·A B OTIS
Dec 1, 1957·The Journal of Clinical Investigation·N R FRANKB G FERRIS
Jul 1, 1958·The American Journal of Medicine·J A PIERCE, R V EBERT
Jan 1, 1964·Journal of Applied Physiology·E SALAZAR, J H KNOWLES
Oct 1, 1964·The British Journal of Radiology·J R EDGEG SIMON
May 1, 1950·Journal of Applied Physiology·A B OTISH RAHN

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Citations

Jan 8, 2016·European Journal of Applied Physiology·Gregory E PeoplesNigel A S Taylor
Aug 11, 2012·Revue de pneumologie clinique·W KetataS Kammoun
Jun 10, 2016·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Glen P KennyAndreas D Flouris
Jun 10, 2016·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Nigel A S TaylorStewart R Petersen
Jan 24, 2018·Journal of Applied Physiology·Yannick Molgat-SeonA William Sheel
Apr 20, 2018·Journal of Applied Physiology·Joshua R SmithThomas P Olson
Sep 24, 2005·Medicine and Science in Sports and Exercise·Kelly-Ann BowlesRungchai Chaunchaiyakul
Jun 14, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Fabien DeruelleClaudine Fabre
Jul 3, 2013·Journal of Applied Physiology·James G HopkerLouis Passfield
Dec 13, 2016·European Journal of Applied Physiology·Lauren A JenkinsJames G Hopker
Jul 10, 2018·Pflügers Archiv : European journal of physiology·Samiya Al-RobaiyBabett Bartling

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