The impact of bariatric surgery on nonalcoholic fatty liver disease

Current Opinion in Clinical Nutrition and Metabolic Care
Alexandre Coutinho Teixeira de FreitasJulio Cezar Uili Coelho

Abstract

To analyze the effects of bariatric surgery on nonalcoholic fatty liver disease by reviewing the most important and recent studies. The prevalence of obesity has increased dramatically over the last decades. Comorbidities related to obesity, such as nonalcoholic fatty liver disease are also increasing. Nonalcoholic fatty liver disease is a progressive disease with potential evolution to liver cirrhosis and hepatocellular carcinoma. Overweight patients who have nonalcoholic fatty liver disease should be considered for a weight loss program; however, long-term result with dietary interventions and drug therapy has been disappointing. Bariatric surgery is effective in promoting long-term weight loss in morbidly obese patients with control of comorbidities, especially those associated with the metabolic syndrome. On the basis of the early experience with extensive intestinal bypass, it was believed that rapid weight loss could cause liver damage. In contrast, recent prospective and retrospective observational studies and case series have demonstrated that bariatric surgery is well tolerated and is associated with nonalcoholic fatty liver disease regression in a significant number of patients. There is good level of evidence that ba...Continue Reading

References

Jan 1, 1978·The Journal of Infectious Diseases·P CorrodiS M Finegold
Mar 1, 1991·Journal of Hepatology·T AndersenP Christoffersen
Feb 7, 1974·The New England Journal of Medicine·R T HolzbachS G Green
Jul 1, 1995·American Journal of Clinical Pathology·E M SilvermanH D Appelman
Aug 1, 1997·Journal of the American College of Surgeons·J A LowellT K Howard
Apr 16, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·F H LuyckxP J Lefèbvre
Apr 18, 1998·Gastroenterology·C P Day, O F James
Nov 21, 1998·Digestive Diseases and Sciences·M P HockingE R Woodward
Mar 3, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S H CaldwellC J Driscoll
May 14, 1999·The Journal of Clinical Endocrinology and Metabolism·P MarceauJ G Kral
May 29, 1999·Gastroenterology·C A MatteoniA J McCullough
Aug 23, 2001·Current Opinion in Clinical Nutrition and Metabolic Care·J C Coelho, A C Campos
Mar 1, 2002·Obesity Surgery·Pierre M GholamLouis J Flancbaum
Aug 29, 2002·Gastroenterology·Samuel KleinHarvey J Sugerman
Jan 28, 2003·Lancet·Joachim SprangerAndreas F H Pfeiffer
Jul 5, 2003·American Journal of Surgery·Ninh T NguyenBruce M Wolfe
Jul 29, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marcelo KugelmasCraig J McClain
Nov 25, 2003·Obesity Surgery·Francesco PapadiaNicola Scopinaro
Feb 26, 2004·Obesity Surgery·Ramsey M DallalPhilip R Schauer
Feb 26, 2004·Obesity Surgery·Aniceto BaltasarMarcelo Bengochea
Jun 9, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·John B DixonPaul E O'Brien
Jul 9, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jason M HuiJacob George
Oct 14, 2004·JAMA : the Journal of the American Medical Association·Henry BuchwaldKaren Schoelles
Dec 24, 2004·The New England Journal of Medicine·Lars SjöströmUNKNOWN Swedish Obese Subjects Study Scientific Group
Dec 30, 2004·Surgical Endoscopy·W S CobbK W Kercher
Jan 5, 2005·Annals of Internal Medicine·Adam Gilden Tsai, Thomas A Wadden
Apr 6, 2005·Annals of Internal Medicine·Zhaoping LiSally C Morton
Oct 4, 2005·Obesity Surgery·Charalabos StratopoulosEvagelos Hadjiyannakis
Dec 13, 2005·Journal of Clinical Gastroenterology·José Guilherme Nogueira da SilvaAytan Miranda Sipahi
Jan 18, 2006·Digestive Diseases and Sciences·K JaskiewiczZ Sledziński
Feb 4, 2006·The American Journal of Gastroenterology·Kevin B BarkerStephen A Harrison

❮ Previous
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Citations

Nov 24, 2011·Obesity Surgery·Myriam MorettoCláudio C Mottin
Nov 1, 2008·Therapeutic Advances in Gastroenterology·Shivakumar Chitturi
Mar 18, 2011·The American Journal of the Medical Sciences·Mona H Ismail
Mar 4, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jia-Huei TsaiRyan M Gill
Jun 28, 2017·World Journal of Hepatology·Mark Benedict, Xuchen Zhang
Oct 21, 2011·Arquivos brasileiros de endocrinologia e metabologia·J B DixonUNKNOWN International Diabetes Federation Taskforce on Epidemiology and Prevention
Mar 6, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity·Kenneth Cusi
Jun 17, 2011·The Cochrane Database of Systematic Reviews·Lijun PengFeng Li
Jul 8, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J A CampbellA J Palmer
Mar 9, 2013·Postgraduate Medical Journal·Simon T AdamsStephen H Leveson
Feb 23, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Francesco Negro

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